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GO Annotations Graph
 Symbol
Name
ID
Fas
Fas (TNF receptor superfamily member 6)
MGI:95484

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
  • Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
  • Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
  • Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
  • Graph generated Wed Jul 23 12:17:05 2014.

CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0042802identical protein bindingISOJ:164563
Molecular FunctionGO:0019900kinase bindingISOJ:164563
Molecular FunctionGO:0002020protease bindingISOJ:155856
Molecular FunctionGO:0005515protein bindingIPIJ:30163
Molecular FunctionGO:0005515protein bindingIPIJ:41242
Molecular FunctionGO:0005515protein bindingIPIJ:65176
Molecular FunctionGO:0005515protein bindingIPIJ:113685
Molecular FunctionGO:0005515protein bindingIPIJ:139785
Molecular FunctionGO:0005515protein bindingIPIJ:166031
Molecular FunctionGO:0005515protein bindingIPIJ:171939
Molecular FunctionGO:0005515protein bindingIPIJ:177240
Molecular FunctionGO:0005515protein bindingIPIJ:184109
Molecular FunctionGO:0005515protein bindingIPIJ:200420
Molecular FunctionGO:0032403protein complex bindingISOJ:155856
Molecular FunctionGO:0004888transmembrane signaling receptor activityIEAJ:72247
Molecular FunctionGO:0005031tumor necrosis factor-activated receptor activityISOJ:155856
Cellular ComponentGO:0097440apical dendriteISOJ:155856
Cellular ComponentGO:0016324apical plasma membraneISOJ:155856
Cellular ComponentGO:0031265CD95 death-inducing signaling complexISOJ:155856
Cellular ComponentGO:0031265CD95 death-inducing signaling complexISOJ:164563
Cellular ComponentGO:0031265CD95 death-inducing signaling complexIDAJ:177240
Cellular ComponentGO:0009986cell surfaceIDAJ:29455
Cellular ComponentGO:0009986cell surfaceISOJ:155856
Cellular ComponentGO:0009986cell surfaceISOJ:164563
Cellular ComponentGO:0005737cytoplasmISOJ:155856
Cellular ComponentGO:0005737cytoplasmISOJ:164563
Cellular ComponentGO:0031264death-inducing signaling complexISOJ:155856
Cellular ComponentGO:0031264death-inducing signaling complexISOJ:164563
Cellular ComponentGO:0009897external side of plasma membraneIDAJ:31364
Cellular ComponentGO:0009897external side of plasma membraneIDAJ:87420
Cellular ComponentGO:0009897external side of plasma membraneIDAJ:104536
Cellular ComponentGO:0009897external side of plasma membraneIDAJ:125784
Cellular ComponentGO:0009897external side of plasma membraneIDAJ:196136
Cellular ComponentGO:0005576extracellular regionIDAJ:29455
Cellular ComponentGO:0005615extracellular spaceISOJ:155856
Cellular ComponentGO:0070062extracellular vesicular exosomeISOJ:164563
Cellular ComponentGO:0016021integral component of membraneIEAJ:60000
Cellular ComponentGO:0016020membraneIEAJ:60000
Cellular ComponentGO:0016020membraneIEAJ:72247
Cellular ComponentGO:0045121membrane raftISOJ:155856
Cellular ComponentGO:0045121membrane raftISOJ:164563
Cellular ComponentGO:0043005neuron projectionISOJ:155856
Cellular ComponentGO:0043025neuronal cell bodyISOJ:155856
Cellular ComponentGO:0005634nucleusISOJ:164563
Cellular ComponentGO:0048471perinuclear region of cytoplasmISOJ:155856
Cellular ComponentGO:0005886plasma membraneISOJ:164563
Cellular ComponentGO:0042383sarcolemmaISOJ:155856
Cellular ComponentGO:0030141secretory granuleISOJ:155856
Biological ProcessGO:0006924activation-induced cell death of T cellsIMPJ:26199
Biological ProcessGO:0006924activation-induced cell death of T cellsIMPJ:31852
Biological ProcessGO:0006924activation-induced cell death of T cellsIDAJ:84826
Biological ProcessGO:0006915apoptotic processIMPJ:34351
Biological ProcessGO:0006915apoptotic processISOJ:73065
Biological ProcessGO:0097190apoptotic signaling pathwayIDAJ:17445
Biological ProcessGO:0097190apoptotic signaling pathwayIDAJ:33466
Biological ProcessGO:0097190apoptotic signaling pathwayISOJ:155856
Biological ProcessGO:0019724B cell mediated immunityIMPJ:131363
Biological ProcessGO:0071455cellular response to hyperoxiaISOJ:164563
Biological ProcessGO:0071285cellular response to lithium ionIMPJ:163720
Biological ProcessGO:0031104dendrite regenerationISOJ:155856
Biological ProcessGO:0097191extrinsic apoptotic signaling pathwayIMPJ:78039
Biological ProcessGO:0097191extrinsic apoptotic signaling pathwayIDAJ:141457
Biological ProcessGO:0097191extrinsic apoptotic signaling pathwayISOJ:164563
Biological ProcessGO:0097192extrinsic apoptotic signaling pathway in absence of ligandIMPJ:85525
Biological ProcessGO:0097192extrinsic apoptotic signaling pathway in absence of ligandIMPJ:85525
Biological ProcessGO:0008625extrinsic apoptotic signaling pathway via death domain receptorsIMPJ:30163
Biological ProcessGO:0008625extrinsic apoptotic signaling pathway via death domain receptorsIDAJ:30163
Biological ProcessGO:0008625extrinsic apoptotic signaling pathway via death domain receptorsIMPJ:56164
Biological ProcessGO:0008625extrinsic apoptotic signaling pathway via death domain receptorsIMPJ:87420
Biological ProcessGO:0008625extrinsic apoptotic signaling pathway via death domain receptorsIDAJ:87420
Biological ProcessGO:0008625extrinsic apoptotic signaling pathway via death domain receptorsIGIJ:88139
Biological ProcessGO:0008625extrinsic apoptotic signaling pathway via death domain receptorsIMPJ:88139
Biological ProcessGO:0008625extrinsic apoptotic signaling pathway via death domain receptorsIDAJ:89131
Biological ProcessGO:0008625extrinsic apoptotic signaling pathway via death domain receptorsIDAJ:113782
Biological ProcessGO:0008625extrinsic apoptotic signaling pathway via death domain receptorsIDAJ:141606
Biological ProcessGO:0008625extrinsic apoptotic signaling pathway via death domain receptorsIDAJ:172906
Biological ProcessGO:0010467gene expressionIMPJ:26199
Biological ProcessGO:0097284hepatocyte apoptotic processIGIJ:209127
Biological ProcessGO:0006955immune responseIEAJ:72247
Biological ProcessGO:0002377immunoglobulin productionIMPJ:131363
Biological ProcessGO:0006925inflammatory cell apoptotic processIDAJ:87420
Biological ProcessGO:0006925inflammatory cell apoptotic processIMPJ:87420
Biological ProcessGO:0097049motor neuron apoptotic processIMPJ:85525
Biological ProcessGO:0097049motor neuron apoptotic processIMPJ:85525
Biological ProcessGO:0097527necroptotic signaling pathwayISOJ:164563
Biological ProcessGO:0097527necroptotic signaling pathwayIGIJ:182381
Biological ProcessGO:0043066negative regulation of apoptotic processIDAJ:29455
Biological ProcessGO:0050869negative regulation of B cell activationIMPJ:7488
Biological ProcessGO:0045060negative thymic T cell selectionIMPJ:56164
Biological ProcessGO:0051402neuron apoptotic processIMPJ:163720
Biological ProcessGO:0043065positive regulation of apoptotic processISOJ:155856
Biological ProcessGO:0043065positive regulation of apoptotic processISOJ:164563
Biological ProcessGO:0010942positive regulation of cell deathISOJ:155856
Biological ProcessGO:0043280positive regulation of cysteine-type endopeptidase activity involved in apoptotic processISOJ:155856
Biological ProcessGO:2001241positive regulation of extrinsic apoptotic signaling pathway in absence of ligandIMPJ:89131
Biological ProcessGO:0032464positive regulation of protein homooligomerizationIDAJ:172906
Biological ProcessGO:0090200positive regulation of release of cytochrome c from mitochondriaICJ:172906
Biological ProcessGO:0051260protein homooligomerizationIDAJ:30163
Biological ProcessGO:0042981regulation of apoptotic processISOJ:155856
Biological ProcessGO:0042127regulation of cell proliferationISOJ:155856
Biological ProcessGO:0010468regulation of gene expressionISOJ:155856
Biological ProcessGO:0045619regulation of lymphocyte differentiationIMPJ:7488
Biological ProcessGO:0045637regulation of myeloid cell differentiationIMPJ:48838
Biological ProcessGO:0003014renal system processIMPJ:31852
Biological ProcessGO:0051384response to glucocorticoidIMPJ:26199
Biological ProcessGO:0051384response to glucocorticoidIMPJ:31852
Biological ProcessGO:0009636response to toxic substanceIMPJ:31382
Biological ProcessGO:0007165signal transductionIEAJ:72247
Biological ProcessGO:0048536spleen developmentIMPJ:131363
Biological ProcessGO:0043029T cell homeostasisIMPJ:31852
Biological ProcessGO:0006927transformed cell apoptotic processIDAJ:87420
Biological ProcessGO:0033209tumor necrosis factor-mediated signaling pathwayISOJ:155856

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IAS Inferred from ancestral seqeuence
  IBA Inferred from biological aspect of ancestor
  IBD Inferred from biological aspect of descendant
  IC Inferred by curator
  IDA Inferred from direct assay
  IEA Inferred from electronic annotation
  IEP Inferred from expression pattern
  IGC Inferred from genomic context
  IGI Inferred from genetic interaction
  IKR Inferred from key residues
  IMP Inferred from mutant phenotype
  IMR Inferred from missing residues
  IPI Inferred from physical interaction
  IRD Inferred from rapid divergence
  ISA Inferred from sequence alignment
  ISM Inferred from sequence model
  ISO Inferred from sequence orthology
  ISS Inferred from sequence or structural similarity
  NAS Non-traceable Author Statement
  ND No biological data available
  RCA Reviewed computational analysis
  TAS Traceable author statement
  NR Obsolete Evidence Code: Not Recorded

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory