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GO Annotations Graph
 Symbol
Name
ID
Apoa2
apolipoprotein A-II
MGI:88050

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
  • Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
  • Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
  • Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
  • Graph generated Fri Jan 17 13:56:29 2014.

CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0034190apolipoprotein receptor bindingISOJ:164563
Molecular FunctionGO:0015485cholesterol bindingISOJ:164563
Molecular FunctionGO:0017127cholesterol transporter activityISOJ:155856
Molecular FunctionGO:0017127contributes_to
cholesterol transporter activity
ISOJ:164563
Molecular FunctionGO:0008035high-density lipoprotein particle bindingIMPJ:88979
Molecular FunctionGO:0070653high-density lipoprotein particle receptor bindingISOJ:164563
Molecular FunctionGO:0055102lipase inhibitor activityISOJ:164563
Molecular FunctionGO:0008289lipid bindingISOJ:164563
Molecular FunctionGO:0005319lipid transporter activityISOJ:164563
Molecular FunctionGO:0031210phosphatidylcholine bindingISOJ:164563
Molecular FunctionGO:0060228phosphatidylcholine-sterol O-acyltransferase activator activityISOJ:164563
Molecular FunctionGO:0005543phospholipid bindingISOJ:164563
Molecular FunctionGO:0046982protein heterodimerization activityISOJ:164563
Molecular FunctionGO:0042803protein homodimerization activityISOJ:164563
Cellular ComponentGO:0042627chylomicronISOJ:164563
Cellular ComponentGO:0005576extracellular regionIEAJ:60000
Cellular ComponentGO:0005576extracellular regionIEAJ:72247
Cellular ComponentGO:0005615extracellular spaceIDAJ:1067
Cellular ComponentGO:0005615extracellular spaceIDAJ:7017
Cellular ComponentGO:0005615extracellular spaceIDAJ:40819
Cellular ComponentGO:0034364high-density lipoprotein particleISOJ:164563
Cellular ComponentGO:0034366spherical high-density lipoprotein particleISOJ:164563
Cellular ComponentGO:0034361very-low-density lipoprotein particleISOJ:164563
Biological ProcessGO:0015759beta-glucoside transportNASJ:116252
Biological ProcessGO:0033344cholesterol effluxISOJ:164563
Biological ProcessGO:0042632cholesterol homeostasisIDAJ:4733
Biological ProcessGO:0042632cholesterol homeostasisIMPJ:55745
Biological ProcessGO:0042632cholesterol homeostasisIGIJ:55745
Biological ProcessGO:0042632cholesterol homeostasisISOJ:164563
Biological ProcessGO:0008203cholesterol metabolic processIMPJ:55745
Biological ProcessGO:0008203cholesterol metabolic processIGIJ:55745
Biological ProcessGO:0008203cholesterol metabolic processIMPJ:76988
Biological ProcessGO:0030301cholesterol transportISOJ:155856
Biological ProcessGO:0046340diacylglycerol catabolic processISOJ:164563
Biological ProcessGO:0006631fatty acid metabolic processNASJ:116252
Biological ProcessGO:0034380high-density lipoprotein particle assemblyISOJ:164563
Biological ProcessGO:0034384high-density lipoprotein particle clearanceISOJ:164563
Biological ProcessGO:0034375high-density lipoprotein particle remodelingISOJ:164563
Biological ProcessGO:0006869lipid transportIMPJ:88979
Biological ProcessGO:0042157lipoprotein metabolic processIDAJ:22520
Biological ProcessGO:0042157lipoprotein metabolic processIDAJ:39861
Biological ProcessGO:0034374low-density lipoprotein particle remodelingISOJ:164563
Biological ProcessGO:0060621negative regulation of cholesterol importISOJ:164563
Biological ProcessGO:0032375negative regulation of cholesterol transportISOJ:164563
Biological ProcessGO:0060695negative regulation of cholesterol transporter activityISOJ:164563
Biological ProcessGO:0002740negative regulation of cytokine secretion involved in immune responseISOJ:164563
Biological ProcessGO:0060192negative regulation of lipase activityIMPJ:55745
Biological ProcessGO:0060192negative regulation of lipase activityISOJ:164563
Biological ProcessGO:0050995negative regulation of lipid catabolic processISOJ:164563
Biological ProcessGO:0010903negative regulation of very-low-density lipoprotein particle remodelingISOJ:164563
Biological ProcessGO:0031100organ regenerationISOJ:155856
Biological ProcessGO:0018206peptidyl-methionine modificationISOJ:164563
Biological ProcessGO:0006656phosphatidylcholine biosynthetic processISOJ:164563
Biological ProcessGO:0009395phospholipid catabolic processISOJ:164563
Biological ProcessGO:0033700phospholipid effluxISOJ:164563
Biological ProcessGO:0043085positive regulation of catalytic activityISOJ:164563
Biological ProcessGO:0010873positive regulation of cholesterol esterificationISOJ:164563
Biological ProcessGO:0045416positive regulation of interleukin-8 biosynthetic processISOJ:164563
Biological ProcessGO:0050996positive regulation of lipid catabolic processISOJ:164563
Biological ProcessGO:0006457protein foldingISOJ:164563
Biological ProcessGO:0018158protein oxidationISOJ:164563
Biological ProcessGO:0030300regulation of intestinal cholesterol absorptionIMPJ:37250
Biological ProcessGO:0031647regulation of protein stabilityISOJ:164563
Biological ProcessGO:0009749response to glucoseISOJ:164563
Biological ProcessGO:0043691reverse cholesterol transportISOJ:164563
Biological ProcessGO:0006810transportIEAJ:60000
Biological ProcessGO:0034370triglyceride-rich lipoprotein particle remodelingISOJ:164563

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IAS Inferred from ancestral seqeuence
  IBA Inferred from biological aspect of ancestor
  IBD Inferred from biological aspect of descendant
  IC Inferred by curator
  IDA Inferred from direct assay
  IEA Inferred from electronic annotation
  IEP Inferred from expression pattern
  IGC Inferred from genomic context
  IGI Inferred from genetic interaction
  IKR Inferred from key residues
  IMP Inferred from mutant phenotype
  IMR Inferred from missing residues
  IPI Inferred from physical interaction
  IRD Inferred from rapid divergence
  ISA Inferred from sequence alignment
  ISM Inferred from sequence model
  ISO Inferred from sequence orthology
  ISS Inferred from sequence or structural similarity
  NAS Non-traceable Author Statement
  ND No biological data available
  RCA Reviewed computational analysis
  TAS Traceable author statement
  NR Obsolete Evidence Code: Not Recorded

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory