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GO Annotations Graph
 Symbol
Name
ID
Gsk3b
glycogen synthase kinase 3 beta
MGI:1861437

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
  • Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
  • Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
  • Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
  • Graph generated Fri Jan 17 13:56:29 2014.

CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0005524ATP bindingISOJ:155856
Molecular FunctionGO:0008013beta-catenin bindingIPIJ:85837
Molecular FunctionGO:0008013beta-catenin bindingISOJ:164563
Molecular FunctionGO:0005178integrin bindingISOJ:155856
Molecular FunctionGO:0035255ionotropic glutamate receptor bindingISOJ:155856
Molecular FunctionGO:0016301kinase activityISOJ:164563
Molecular FunctionGO:0051059NF-kappaB bindingISOJ:164563
Molecular FunctionGO:0000166nucleotide bindingIEAJ:60000
Molecular FunctionGO:0002039p53 bindingISOJ:73065
Molecular FunctionGO:0005515protein bindingIPIJ:47363
Molecular FunctionGO:0005515protein bindingIPIJ:80922
Molecular FunctionGO:0005515protein bindingIPIJ:83886
Molecular FunctionGO:0005515protein bindingIPIJ:105811
Molecular FunctionGO:0005515protein bindingIPIJ:112696
Molecular FunctionGO:0005515protein bindingIPIJ:115106
Molecular FunctionGO:0005515protein bindingIPIJ:117258
Molecular FunctionGO:0005515protein bindingIPIJ:141207
Molecular FunctionGO:0005515protein bindingIPIJ:147223
Molecular FunctionGO:0005515protein bindingIPIJ:147568
Molecular FunctionGO:0005515protein bindingIPIJ:161722
Molecular FunctionGO:0005515protein bindingIPIJ:164860
Molecular FunctionGO:0005515protein bindingIPIJ:166010
Molecular FunctionGO:0005515protein bindingIPIJ:171976
Molecular FunctionGO:0005515protein bindingIPIJ:180612
Molecular FunctionGO:0005515protein bindingIPIJ:183670
Molecular FunctionGO:0034236protein kinase A catalytic subunit bindingISOJ:164563
Molecular FunctionGO:0004672protein kinase activityIDAJ:87871
Molecular FunctionGO:0019901protein kinase bindingISOJ:155856
Molecular FunctionGO:0019901protein kinase bindingISOJ:164563
Molecular FunctionGO:0004674protein serine/threonine kinase activityISSJ:63274
Molecular FunctionGO:0004674protein serine/threonine kinase activityISOJ:73065
Molecular FunctionGO:0004674protein serine/threonine kinase activityISOJ:73065
Molecular FunctionGO:0004674protein serine/threonine kinase activityIDAJ:83886
Molecular FunctionGO:0004674protein serine/threonine kinase activityIDAJ:135361
Molecular FunctionGO:0004674protein serine/threonine kinase activityISOJ:155856
Molecular FunctionGO:0004674protein serine/threonine kinase activityIDAJ:161722
Molecular FunctionGO:0004674protein serine/threonine kinase activityIDAJ:180612
Molecular FunctionGO:0004674protein serine/threonine kinase activityIDAJ:187651
Molecular FunctionGO:0004674protein serine/threonine kinase activityIMPJ:201566
Molecular FunctionGO:0001085RNA polymerase II transcription factor bindingISOJ:164563
Molecular FunctionGO:0048156tau protein bindingISOJ:155856
Molecular FunctionGO:0050321tau-protein kinase activityIDAJ:91529
Molecular FunctionGO:0050321tau-protein kinase activityISOJ:155856
Molecular FunctionGO:0050321tau-protein kinase activityISOJ:164563
Molecular FunctionGO:0016740transferase activityIEAJ:60000
Molecular FunctionGO:0016772transferase activity, transferring phosphorus-containing groupsIEAJ:72247
Molecular FunctionGO:0031625ubiquitin protein ligase bindingISOJ:164563
Cellular ComponentGO:0030877beta-catenin destruction complexIDAJ:54993
Cellular ComponentGO:0030877beta-catenin destruction complexISOJ:155856
Cellular ComponentGO:0030877beta-catenin destruction complexISOJ:164563
Cellular ComponentGO:0005813centrosomeISOJ:164563
Cellular ComponentGO:0005737cytoplasmISOJ:73065
Cellular ComponentGO:0005737cytoplasmISOJ:155856
Cellular ComponentGO:0005829cytosolIDAJ:81172
Cellular ComponentGO:0005829cytosolISOJ:155856
Cellular ComponentGO:0043198dendritic shaftIDAJ:83886
Cellular ComponentGO:0043197dendritic spineISOJ:155856
Cellular ComponentGO:0030426growth coneIDAJ:83886
Cellular ComponentGO:0016020membraneISOJ:155856
Cellular ComponentGO:0045121membrane raftISOJ:155856
Cellular ComponentGO:0043227membrane-bounded organelleIDAJ:83886
Cellular ComponentGO:0043025neuronal cell bodyIDAJ:83886
Cellular ComponentGO:0005634nucleusISOJ:73065
Cellular ComponentGO:0005634nucleusIDAJ:81172
Cellular ComponentGO:0005634nucleusISOJ:155856
Cellular ComponentGO:0005634nucleusIDAJ:183670
Cellular ComponentGO:0048471perinuclear region of cytoplasmIDAJ:165329
Cellular ComponentGO:0005886plasma membraneISOJ:164563
Cellular ComponentGO:0043234protein complexISOJ:155856
Cellular ComponentGO:0030529ribonucleoprotein complexIDAJ:174389
Biological ProcessGO:0007409axonogenesisIGIJ:138829
Biological ProcessGO:0060070canonical Wnt signaling pathwayIDAJ:95052
Biological ProcessGO:0060070canonical Wnt signaling pathwayISOJ:164563
Biological ProcessGO:0044337canonical Wnt signaling pathway involved in positive regulation of apoptotic processIMPJ:163141
Biological ProcessGO:0005975carbohydrate metabolic processIEAJ:60000
Biological ProcessGO:0030154cell differentiationIEAJ:60000
Biological ProcessGO:0016477cell migrationIGIJ:135361
Biological ProcessGO:0008283cell proliferationTASJ:63274
Biological ProcessGO:0036016cellular response to interleukin-3IDAJ:201566
Biological ProcessGO:0071260cellular response to mechanical stimulusISOJ:155856
Biological ProcessGO:0007623circadian rhythmIMPJ:161722
Biological ProcessGO:0007010cytoskeleton organizationTASJ:180612
Biological ProcessGO:0001837epithelial to mesenchymal transitionISOJ:164563
Biological ProcessGO:0006983ER overload responseISOJ:73065
Biological ProcessGO:0006983ER overload responseIDAJ:88275
Biological ProcessGO:0030010establishment of cell polarityISOJ:155856
Biological ProcessGO:0007163establishment or maintenance of cell polarityISOJ:155856
Biological ProcessGO:0097192extrinsic apoptotic signaling pathway in absence of ligandIDAJ:201566
Biological ProcessGO:0045444fat cell differentiationIDAJ:81172
Biological ProcessGO:0005977glycogen metabolic processISOJ:164563
Biological ProcessGO:0021766hippocampus developmentISOJ:164563
Biological ProcessGO:0044027hypermethylation of CpG islandIMPJ:173141
Biological ProcessGO:0035556intracellular signal transductionISOJ:87682
Biological ProcessGO:0007275multicellular organismal developmentIEAJ:60000
Biological ProcessGO:0007520myoblast fusionIDAJ:95052
Biological ProcessGO:0007520myoblast fusionIGIJ:95052
Biological ProcessGO:0014902myotube differentiationIGIJ:95052
Biological ProcessGO:0043066negative regulation of apoptotic processIMPJ:63274
Biological ProcessGO:0043066negative regulation of apoptotic processISOJ:73065
Biological ProcessGO:0010614negative regulation of cardiac muscle hypertrophyIDAJ:73985
Biological ProcessGO:0050774negative regulation of dendrite morphogenesisISOJ:155856
Biological ProcessGO:0043407negative regulation of MAP kinase activityISOJ:155856
Biological ProcessGO:0051534negative regulation of NFAT protein import into nucleusISOJ:164563
Biological ProcessGO:0032091negative regulation of protein bindingISOJ:164563
Biological ProcessGO:0031333negative regulation of protein complex assemblyISOJ:164563
Biological ProcessGO:0009968negative regulation of signal transductionIEAJ:60000
Biological ProcessGO:0007399nervous system developmentIEAJ:60000
Biological ProcessGO:0009887organ morphogenesisIMPJ:63274
Biological ProcessGO:0018105peptidyl-serine phosphorylationISOJ:73065
Biological ProcessGO:0018105peptidyl-serine phosphorylationISOJ:73065
Biological ProcessGO:0018105peptidyl-serine phosphorylationIDAJ:135361
Biological ProcessGO:0018105peptidyl-serine phosphorylationIDAJ:161722
Biological ProcessGO:0016310phosphorylationIMPJ:117258
Biological ProcessGO:0043065positive regulation of apoptotic processISOJ:155856
Biological ProcessGO:0001954positive regulation of cell-matrix adhesionISOJ:164563
Biological ProcessGO:1901030positive regulation of mitochondrial outer membrane permeabilizationIDAJ:201566
Biological ProcessGO:0033138positive regulation of peptidyl-serine phosphorylationIDAJ:135361
Biological ProcessGO:0010800positive regulation of peptidyl-threonine phosphorylationIDAJ:135361
Biological ProcessGO:0032436positive regulation of proteasomal ubiquitin-dependent protein catabolic processIGIJ:187651
Biological ProcessGO:0032092positive regulation of protein bindingIDAJ:148434
Biological ProcessGO:0031334positive regulation of protein complex assemblyISOJ:164563
Biological ProcessGO:0046827positive regulation of protein export from nucleusISOJ:73065
Biological ProcessGO:0032855positive regulation of Rac GTPase activityISOJ:164563
Biological ProcessGO:2000738positive regulation of stem cell differentiationIMPJ:183670
Biological ProcessGO:0045944positive regulation of transcription from RNA polymerase II promoterIMPJ:173141
Biological ProcessGO:0006611protein export from nucleusIDAJ:73985
Biological ProcessGO:0035372protein localization to microtubuleIGIJ:138829
Biological ProcessGO:0006468protein phosphorylationISSJ:63274
Biological ProcessGO:0006468protein phosphorylationIDAJ:80922
Biological ProcessGO:0006468protein phosphorylationIDAJ:83886
Biological ProcessGO:0006468protein phosphorylationIDAJ:87871
Biological ProcessGO:0006468protein phosphorylationIDAJ:114505
Biological ProcessGO:0006468protein phosphorylationIGIJ:148434
Biological ProcessGO:0006468protein phosphorylationISOJ:155856
Biological ProcessGO:0006468protein phosphorylationISOJ:164563
Biological ProcessGO:0006468protein phosphorylationIMPJ:201566
Biological ProcessGO:0000320re-entry into mitotic cell cycleIDAJ:81172
Biological ProcessGO:0006349regulation of gene expression by genetic imprintingIMPJ:173141
Biological ProcessGO:0032886regulation of microtubule-based processISOJ:164563
Biological ProcessGO:0032886regulation of microtubule-based processIDAJ:170927
Biological ProcessGO:0048168regulation of neuronal synaptic plasticityISOJ:155856
Biological ProcessGO:0071109superior temporal gyrus developmentISOJ:164563
Biological ProcessGO:0016055Wnt signaling pathwayIGIJ:110693
Biological ProcessGO:0016055Wnt signaling pathwayIGIJ:192364

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IAS Inferred from ancestral seqeuence
  IBA Inferred from biological aspect of ancestor
  IBD Inferred from biological aspect of descendant
  IC Inferred by curator
  IDA Inferred from direct assay
  IEA Inferred from electronic annotation
  IEP Inferred from expression pattern
  IGC Inferred from genomic context
  IGI Inferred from genetic interaction
  IKR Inferred from key residues
  IMP Inferred from mutant phenotype
  IMR Inferred from missing residues
  IPI Inferred from physical interaction
  IRD Inferred from rapid divergence
  ISA Inferred from sequence alignment
  ISM Inferred from sequence model
  ISO Inferred from sequence orthology
  ISS Inferred from sequence or structural similarity
  NAS Non-traceable Author Statement
  ND No biological data available
  RCA Reviewed computational analysis
  TAS Traceable author statement
  NR Obsolete Evidence Code: Not Recorded

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory