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GO Annotations Graph
 Symbol
Name
ID
Ash2l
ash2 (absent, small, or homeotic)-like (Drosophila)
MGI:1344416

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
  • Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
  • Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
  • Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
  • Graph generated Wed Jul 23 12:17:05 2014.

CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0003677DNA bindingIEAJ:60000
Molecular FunctionGO:0042800contributes_to
histone methyltransferase activity (H3-K4 specific)
ISOJ:164563
Molecular FunctionGO:0046872metal ion bindingIEAJ:60000
Molecular FunctionGO:0005515protein bindingIPIJ:131452
Molecular FunctionGO:0005515protein bindingIPIJ:162660
Molecular FunctionGO:0005515protein bindingIPIJ:171270
Molecular FunctionGO:0005515protein bindingIPIJ:175308
Molecular FunctionGO:0005515protein bindingIPIJ:182375
Molecular FunctionGO:0044212transcription regulatory region DNA bindingISOJ:164563
Cellular ComponentGO:0035097histone methyltransferase complexISOJ:73065
Cellular ComponentGO:0035097histone methyltransferase complexISOJ:123598
Cellular ComponentGO:0071339MLL1 complexIDAJ:156231
Cellular ComponentGO:0005634nucleusISOJ:123598
Cellular ComponentGO:0005634nucleusISOJ:164563
Cellular ComponentGO:0048188Set1C/COMPASS complexISOJ:164563
Biological ProcessGO:0006974cellular response to DNA damage stimulusISOJ:123598
Biological ProcessGO:0016568chromatin modificationIEAJ:60000
Biological ProcessGO:0051568histone H3-K4 methylationISOJ:164563
Biological ProcessGO:0008284positive regulation of cell proliferationISOJ:164563
Biological ProcessGO:0045944positive regulation of transcription from RNA polymerase II promoterIGIJ:162660
Biological ProcessGO:0006355regulation of transcription, DNA-templatedIEAJ:60000
Biological ProcessGO:0043627response to estrogenISOJ:164563
Biological ProcessGO:0006351transcription, DNA-templatedIEAJ:60000

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IAS Inferred from ancestral seqeuence
  IBA Inferred from biological aspect of ancestor
  IBD Inferred from biological aspect of descendant
  IC Inferred by curator
  IDA Inferred from direct assay
  IEA Inferred from electronic annotation
  IEP Inferred from expression pattern
  IGC Inferred from genomic context
  IGI Inferred from genetic interaction
  IKR Inferred from key residues
  IMP Inferred from mutant phenotype
  IMR Inferred from missing residues
  IPI Inferred from physical interaction
  IRD Inferred from rapid divergence
  ISA Inferred from sequence alignment
  ISM Inferred from sequence model
  ISO Inferred from sequence orthology
  ISS Inferred from sequence or structural similarity
  NAS Non-traceable Author Statement
  ND No biological data available
  RCA Reviewed computational analysis
  TAS Traceable author statement
  NR Obsolete Evidence Code: Not Recorded

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory