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GO Annotations Graph
 Symbol
Name
ID
Acvrl1
activin A receptor, type II-like 1
MGI:1338946

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
  • Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
  • Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
  • Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
  • Graph generated Wed Jul 23 12:17:05 2014.

CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0048185activin bindingISOJ:164563
Molecular FunctionGO:0016361activin receptor activity, type IISOJ:73065
Molecular FunctionGO:0005524ATP bindingISOJ:164563
Molecular FunctionGO:0016301kinase activityIEAJ:60000
Molecular FunctionGO:0046872metal ion bindingIEAJ:60000
Molecular FunctionGO:0000166nucleotide bindingIEAJ:60000
Molecular FunctionGO:0005515protein bindingIPIJ:86237
Molecular FunctionGO:0005515protein bindingIPIJ:164086
Molecular FunctionGO:0004672protein kinase activityIEAJ:72247
Molecular FunctionGO:0019901protein kinase bindingISOJ:164563
Molecular FunctionGO:0004674protein serine/threonine kinase activityISOJ:164563
Molecular FunctionGO:0004702receptor signaling protein serine/threonine kinase activityISOJ:155856
Molecular FunctionGO:0046332SMAD bindingISOJ:155856
Molecular FunctionGO:0046332SMAD bindingISOJ:164563
Molecular FunctionGO:0016740transferase activityIEAJ:60000
Molecular FunctionGO:0016772transferase activity, transferring phosphorus-containing groupsIEAJ:72247
Molecular FunctionGO:0050431transforming growth factor beta bindingISOJ:164563
Molecular FunctionGO:0005025transforming growth factor beta receptor activity, type IISOJ:155856
Molecular FunctionGO:0005025contributes_to
transforming growth factor beta receptor activity, type I
ISOJ:164563
Molecular FunctionGO:0005024transforming growth factor beta-activated receptor activityISOJ:73065
Molecular FunctionGO:0004675transmembrane receptor protein serine/threonine kinase activityIEAJ:72247
Cellular ComponentGO:0009986cell surfaceISOJ:73065
Cellular ComponentGO:0030425dendriteISOJ:155856
Cellular ComponentGO:0016021integral component of membraneIEAJ:60000
Cellular ComponentGO:0005887integral component of plasma membraneISOJ:164563
Cellular ComponentGO:0016020membraneIEAJ:60000
Cellular ComponentGO:0016020membraneIEAJ:72247
Cellular ComponentGO:0043025neuronal cell bodyISOJ:155856
Biological ProcessGO:0032924activin receptor signaling pathwayISOJ:73065
Biological ProcessGO:0001525angiogenesisIMPJ:61177
Biological ProcessGO:0001525angiogenesisIMPJ:65521
Biological ProcessGO:0001525angiogenesisISOJ:164563
Biological ProcessGO:0060840artery developmentIMPJ:157791
Biological ProcessGO:0008015blood circulationISOJ:164563
Biological ProcessGO:0048514blood vessel morphogenesisIMPJ:122868
Biological ProcessGO:0048514blood vessel morphogenesisIMPJ:130020
Biological ProcessGO:0001974blood vessel remodelingIMPJ:157791
Biological ProcessGO:0030509BMP signaling pathwayISOJ:164563
Biological ProcessGO:0030509BMP signaling pathwayIMPJ:186473
Biological ProcessGO:0071773cellular response to BMP stimulusISOJ:164563
Biological ProcessGO:0071560cellular response to transforming growth factor beta stimulusIDAJ:149284
Biological ProcessGO:0071560cellular response to transforming growth factor beta stimulusISOJ:164563
Biological ProcessGO:0042118endothelial cell activationTASJ:164086
Biological ProcessGO:0061154endothelial tube morphogenesisISOJ:164563
Biological ProcessGO:0001701in utero embryonic developmentIMPJ:130020
Biological ProcessGO:0035556intracellular signal transductionISOJ:155856
Biological ProcessGO:0001946lymphangiogenesisIMPJ:157791
Biological ProcessGO:0060836lymphatic endothelial cell differentiationIMPJ:157791
Biological ProcessGO:0060836lymphatic endothelial cell differentiationISOJ:164563
Biological ProcessGO:0043537negative regulation of blood vessel endothelial cell migrationISOJ:164563
Biological ProcessGO:0007162negative regulation of cell adhesionISOJ:164563
Biological ProcessGO:0030308negative regulation of cell growthISOJ:164563
Biological ProcessGO:0030336negative regulation of cell migrationISOJ:164563
Biological ProcessGO:0008285negative regulation of cell proliferationISOJ:164563
Biological ProcessGO:2000279negative regulation of DNA biosynthetic processISOJ:164563
Biological ProcessGO:0045602negative regulation of endothelial cell differentiationIDAJ:164086
Biological ProcessGO:0010596negative regulation of endothelial cell migrationISOJ:164563
Biological ProcessGO:0001937negative regulation of endothelial cell proliferationIDAJ:164086
Biological ProcessGO:0051895negative regulation of focal adhesion assemblyISOJ:164563
Biological ProcessGO:0016310phosphorylationIEAJ:60000
Biological ProcessGO:0045766positive regulation of angiogenesisIGIJ:204744
Biological ProcessGO:0030513positive regulation of BMP signaling pathwayIDAJ:164086
Biological ProcessGO:0030513positive regulation of BMP signaling pathwayISOJ:164563
Biological ProcessGO:0045603positive regulation of endothelial cell differentiationIDAJ:164086
Biological ProcessGO:0001938positive regulation of endothelial cell proliferationIDAJ:164086
Biological ProcessGO:0010862positive regulation of pathway-restricted SMAD protein phosphorylationISOJ:164563
Biological ProcessGO:0045944positive regulation of transcription from RNA polymerase II promoterISOJ:164563
Biological ProcessGO:0045893positive regulation of transcription, DNA-templatedIMPJ:164086
Biological ProcessGO:0045893positive regulation of transcription, DNA-templatedISOJ:164563
Biological ProcessGO:0051291protein heterooligomerizationISOJ:155856
Biological ProcessGO:0006468protein phosphorylationISOJ:155856
Biological ProcessGO:0006468protein phosphorylationISOJ:164563
Biological ProcessGO:0008217regulation of blood pressureISOJ:164563
Biological ProcessGO:0006355regulation of transcription, DNA-templatedISOJ:164563
Biological ProcessGO:0061298retina vasculature development in camera-type eyeIMPJ:157791
Biological ProcessGO:0007165signal transductionISOJ:164563
Biological ProcessGO:0023014signal transduction by phosphorylationISOJ:155856
Biological ProcessGO:0007179transforming growth factor beta receptor signaling pathwayIDAJ:86237
Biological ProcessGO:0007179transforming growth factor beta receptor signaling pathwayISOJ:155856
Biological ProcessGO:0007179transforming growth factor beta receptor signaling pathwayISOJ:164563
Biological ProcessGO:0007178transmembrane receptor protein serine/threonine kinase signaling pathwayIEAJ:72247
Biological ProcessGO:0060841venous blood vessel developmentIMPJ:157791
Biological ProcessGO:0035313wound healing, spreading of epidermal cellsISOJ:164563

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IAS Inferred from ancestral seqeuence
  IBA Inferred from biological aspect of ancestor
  IBD Inferred from biological aspect of descendant
  IC Inferred by curator
  IDA Inferred from direct assay
  IEA Inferred from electronic annotation
  IEP Inferred from expression pattern
  IGC Inferred from genomic context
  IGI Inferred from genetic interaction
  IKR Inferred from key residues
  IMP Inferred from mutant phenotype
  IMR Inferred from missing residues
  IPI Inferred from physical interaction
  IRD Inferred from rapid divergence
  ISA Inferred from sequence alignment
  ISM Inferred from sequence model
  ISO Inferred from sequence orthology
  ISS Inferred from sequence or structural similarity
  NAS Non-traceable Author Statement
  ND No biological data available
  RCA Reviewed computational analysis
  TAS Traceable author statement
  NR Obsolete Evidence Code: Not Recorded

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory