Phenotype Images associated with this Gene

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Phenotype Images associated with this Gene

Symbol
Name
ID

Runx2
runt related transcription factor 2
MGI:99829

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Click on allele symbol for full phenotype details.

	Caption: Runx2^tm1Hkiy/Runx2⁺ and Runx2^tm1Hkiy/Runx2^tm1Hkiy mice show delayed bone ossification (details) Represented Alleles: Runx2^tm1Hkiy, runt related transcription factor 2; targeted mutation 1, Hiroshi Kiyono Copyright: This image is from Okura H, PLoS One 2014;9(9):e108294, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:223410
	Caption: Decreased bone density in Runx2^tm1Hkiy/Runx2^tm1Hkiy mice but not Runx2^tm1Hkiy/Runx2⁺ mice (details) Represented Alleles: Runx2^tm1Hkiy, runt related transcription factor 2; targeted mutation 1, Hiroshi Kiyono Copyright: This image is from Okura H, PLoS One 2014;9(9):e108294, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:223410
	Caption: Trabecular bone and clavicle analysis in various mice with Runx2^tm1Mjo and/or Hivep3^tm1Glm alleles (details) Represented Alleles: Hivep3^tm1Glm, human immunodeficiency virus type I enhancer binding protein 3; targeted mutation 1, Laurie H Glimcher Runx2^tm1Mjo, runt related transcription factor 2; targeted mutation 1, Michael J Owen Copyright: This image is from Shim JH, J Clin Invest 2013 Sep 3;123(9):4010-22 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:201597
	Caption: Calvaria and clavicle abnormalities in Gsk3b^tm1Jrw/Gsk3b⁺, Runx2^tm1Kish/Runx2⁺, and Gsk3b^tm1Jrw/Gsk3b⁺ Runx2^tm1Kish/Runx2⁺ mice (details) Represented Alleles: Gsk3b^tm1Jrw, glycogen synthase kinase 3 beta; targeted mutation 1, James R Woodgett Runx2^tm1Kish, runt related transcription factor 2; targeted mutation 1, Tadamitsu Kishimoto Copyright: This image is from Kugimiya F, PLoS ONE 2007;2(9):e837, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:129364
	Caption: Smaller body size and perinatal mortality in Runx2^tm1Ldq/Runx2^tm1Ldq mice (details) Represented Alleles: Runx2^tm1Ldq, runt related transcription factor 2; targeted mutation 1, L Darryl Quarles Copyright: This image is from Xiao ZS, J Biol Chem 2004 May 7;279(19):20307-13 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:89822
	Caption: Skeletal abnormalities in Runx2^tm1Ldq/Runx2^tm1Ldq newborn mice (details) Represented Alleles: Runx2^tm1Ldq, runt related transcription factor 2; targeted mutation 1, L Darryl Quarles Copyright: This image is from Xiao ZS, J Biol Chem 2004 May 7;279(19):20307-13 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:89822
	Caption: Decrease in trabecular and cortical thickness in Runx2^tm1Ldq/Runx2⁺ and Runx2^tm1Ldq/Runx2^tm1Ldq tibia (details) Represented Alleles: Runx2^tm1Ldq, runt related transcription factor 2; targeted mutation 1, L Darryl Quarles Copyright: This image is from Xiao ZS, J Biol Chem 2004 May 7;279(19):20307-13 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:89822
	Caption: Embryonic lethality in Runx2^tm1Gss/Runx2^tm1Gss and absence of clavicle in Runx2^tm1Gss/Runx2⁺ mice (details) Represented Alleles: Runx2^tm1Gss, runt related transcription factor 2; targeted mutation 1, Gary S Stein Copyright: This image is from Choi JY, Proc Natl Acad Sci U S A 2001 Jul 17;98(15):8650-5. Copyright 2001 National Academy of Sciences, U.S.A. J:70461
	Caption: Absence of bone tissues in the Runx2^tm1Gss/Runx2^tm1Gss mouse (details) Represented Alleles: Runx2^tm1Gss, runt related transcription factor 2; targeted mutation 1, Gary S Stein Copyright: This image is from Choi JY, Proc Natl Acad Sci U S A 2001 Jul 17;98(15):8650-5. Copyright 2001 National Academy of Sciences, U.S.A. J:70461

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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