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Phenotype Images associated with this Gene
Symbol
Name
ID
Tgfb1
transforming growth factor, beta 1
MGI:98725


11 phenotype image(s) for Tgfb1 alleles
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Caption: Reduced size, kyphosis, tooth abnormalities, and decreased mineral density and dental attrition in Tgfb1tm1(Tgfb3)Kul/Tgfb1tm1(Tgfb3)Kul mice (details)
Represented Alleles:
Tgfb1tm1(Tgfb3)Kul, transforming growth factor, beta 1; targeted mutation 1, Ashok B Kulkarni
Copyright: This image is from Hall BE, J Biol Chem 2013 Nov 1;288(44):32074-92 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:204892
Caption: Defects in secondary ossification in Tgfb1tm1(Tgfb3)Kul/Tgfb1tm1(Tgfb3)Kul mice (details)
Represented Alleles:
Tgfb1tm1(Tgfb3)Kul, transforming growth factor, beta 1; targeted mutation 1, Ashok B Kulkarni
Copyright: This image is from Hall BE, J Biol Chem 2013 Nov 1;288(44):32074-92 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:204892
Caption: Tgfb1tm1(Tgfb3)Kul/Tgfb1tm1(Tgfb3)Kul mice remain small and thin on a high fat dough diet (details)
Represented Alleles:
Tgfb1tm1(Tgfb3)Kul, transforming growth factor, beta 1; targeted mutation 1, Ashok B Kulkarni
Copyright: This image is from Hall BE, J Biol Chem 2013 Nov 1;288(44):32074-92 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:204892
Caption: Reduction in adipose tissue underlying the skin dermis, reduced adipocyte size and no development of steatosis in Tgfb1tm1(Tgfb3)Kul/Tgfb1tm1(Tgfb3)Kul mice fed a high fat dough diet (details)
Represented Alleles:
Tgfb1tm1(Tgfb3)Kul, transforming growth factor, beta 1; targeted mutation 1, Ashok B Kulkarni
Copyright: This image is from Hall BE, J Biol Chem 2013 Nov 1;288(44):32074-92 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:204892
Caption: Lung and salivary gland inflammation in Tgfb1tm2.1Doe/Tgfb1tm2.1Doe Tg(Lck-cre)548Jxm/? (b,e) and Tgfb1tm1Doe/Tgfb1tm2.1Doe Tg(Lck-cre)548Jxm/? (c,f) mice (details)
Represented Alleles:
Tgfb1tm1Doe, transforming growth factor, beta 1; targeted mutation 1, Thomas Doetschman
Tgfb1tm2.1Doe, transforming growth factor, beta 1; targeted mutation 2.1, Thomas Doetschman
Tg(Lck-cre)548Jxm, transgene insertion 548, Jamey Marth
Copyright: This image is from Azhar M, Genesis 2009 Jun;47(6):423-31, and is displayed with the permission of Wiley-Blackwell, who owns the Copyright. J:150024
Caption: Tgfb1tm1Jmu/Tgfb1tm1Jmu mice develop fatal multiorgan inflammation (details)
Represented Alleles:
Tgfb1tm1Jmu, transforming growth factor, beta 1; targeted mutation 1, John Munger
Copyright: This image is from Yang Z, J Cell Biol 2007 Mar 12;176(6):787-93, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:120085
Caption: Abnormal vascular development in Tgfb1tm1Jmu/Tgfb1tm1Jmu mice and fewer Langerhans cells in Tgfb1tm1Jmu/Tgfb1tm1Jmu and Itgb6tm1Des/Itgb6tm1Des mice (details)
Represented Alleles:
Itgb6tm1Des, integrin beta 6; targeted mutation 1, Dean Sheppard
Tgfb1tm1Jmu, transforming growth factor, beta 1; targeted mutation 1, John Munger
Copyright: This image is from Yang Z, J Cell Biol 2007 Mar 12;176(6):787-93, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:120085
Caption: Gross tooth abnormalities in Tg(Dspp-TGFB1)3Kul/? mice (details)
Represented Alleles:
Tg(Dspp-TGFB1)3Kul, transgene insertion 3, Ashok B Kulkarni
Copyright: This image is from Thyagarajan T, J Biol Chem 2001 Apr 6;276(14):11016-20 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:118918
Caption: Tg(Dspp-TGFB1)3Kul/? molars exhibit an irregular odontoblast layer and dentinal tubules with cellular inclusions (details)
Represented Alleles:
Tg(Dspp-TGFB1)3Kul, transgene insertion 3, Ashok B Kulkarni
Copyright: This image is from Thyagarajan T, J Biol Chem 2001 Apr 6;276(14):11016-20 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:118918
Caption: Tg(Dspp-TGFB1)3Kul/? teeth exhibit abnormal and irregular dentin (details)
Represented Alleles:
Tg(Dspp-TGFB1)3Kul, transgene insertion 3, Ashok B Kulkarni
Copyright: This image is from Thyagarajan T, J Biol Chem 2001 Apr 6;276(14):11016-20 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:118918

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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory