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Phenotype Images associated with this Gene
Symbol
Name
ID
Pkd1
polycystin 1, transient receptor poteintial channel interacting
MGI:97603


38 phenotype image(s) for Pkd1 alleles
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Caption: Kidney cysts in Pkd1tm1.1Pcha/Pkd1tm1.1Pcha mice (details)
Represented Alleles:
Pkd1tm1.1Pcha, polycystin 1, transient receptor poteintial channel interacting; targeted mutation 1.1, Peter Harris
Copyright: This image is from Hopp K, J Clin Invest 2012 Nov 1;122(11):4257-73 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:193544
Caption: Polycystic kidney disease in Pkd1tm1.1Pcha/Pkd1tm1.1Pcha mice (details)
Represented Alleles:
Pkd1tm1.1Pcha, polycystin 1, transient receptor poteintial channel interacting; targeted mutation 1.1, Peter Harris
Copyright: This image is from Hopp K, J Clin Invest 2012 Nov 1;122(11):4257-73 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:193544
Caption: Pkd1tm1.1Pcha/Pkd1tm1Shh mice develop in utero/early-onset autosomal dominant polycystic kidney disease (details)
Represented Alleles:
Pkd1tm1.1Pcha, polycystin 1, transient receptor poteintial channel interacting; targeted mutation 1.1, Peter Harris
Pkd1tm1Shh, polycystin 1, transient receptor poteintial channel interacting; targeted mutation 1, Shigeo Horie
Copyright: This image is from Hopp K, J Clin Invest 2012 Nov 1;122(11):4257-73 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:193544
Caption: Pkd1tm1.1Pcha/Pkd1tm1Shh mice show early-onset and rapidly progressive cystic disease (details)
Represented Alleles:
Pkd1tm1.1Pcha, polycystin 1, transient receptor poteintial channel interacting; targeted mutation 1.1, Peter Harris
Pkd1tm1Shh, polycystin 1, transient receptor poteintial channel interacting; targeted mutation 1, Shigeo Horie
Copyright: This image is from Hopp K, J Clin Invest 2012 Nov 1;122(11):4257-73 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:193544
Caption: Pkd1tm1.1Pcha/Pkd1tm1.1Pcha and Pkd1tm1.1Pcha/Pkd1tm1Shh mice show a switch in tubular cyst origin (from proximal tubule to collecting duct) corresponding to age (details)
Represented Alleles:
Pkd1tm1.1Pcha, polycystin 1, transient receptor poteintial channel interacting; targeted mutation 1.1, Peter Harris
Pkd1tm1Shh, polycystin 1, transient receptor poteintial channel interacting; targeted mutation 1, Shigeo Horie
Copyright: This image is from Hopp K, J Clin Invest 2012 Nov 1;122(11):4257-73 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:193544
Caption: Primary cilia are elongated in Pkd1tm1.1Pcha/Pkd1tm1.1Pcha and Pkd1tm1.1Pcha/Pkd1tm1Shh collecting ducts (details)
Represented Alleles:
Pkd1tm1.1Pcha, polycystin 1, transient receptor poteintial channel interacting; targeted mutation 1.1, Peter Harris
Pkd1tm1Shh, polycystin 1, transient receptor poteintial channel interacting; targeted mutation 1, Shigeo Horie
Copyright: This image is from Hopp K, J Clin Invest 2012 Nov 1;122(11):4257-73 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:193544
Caption: Illustration of polycystic kidney disease progression and variation in Pkd1tm1.1Pcha/Pkd1tm1.1Pcha mice (details)
Represented Alleles:
Pkd1tm1.1Pcha, polycystin 1, transient receptor poteintial channel interacting; targeted mutation 1.1, Peter Harris
Copyright: This image is from Hopp K, J Clin Invest 2012 Nov 1;122(11):4257-73 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:193544
Caption: Cyst development during embryogenesis and the first postnatal month in Pkd1tm1.1Pcha/Pkd1tm1.1Pcha and Pkd1tm1.1Pcha/Pkd1tm1Shh animals (details)
Represented Alleles:
Pkd1tm1.1Pcha, polycystin 1, transient receptor poteintial channel interacting; targeted mutation 1.1, Peter Harris
Pkd1tm1Shh, polycystin 1, transient receptor poteintial channel interacting; targeted mutation 1, Shigeo Horie
Copyright: This image is from Hopp K, J Clin Invest 2012 Nov 1;122(11):4257-73 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:193544
Caption: Illustration of kidney cyst disease variation in Pkd1tm1.1Pcha/Pkd1tm1Shh mice (details)
Represented Alleles:
Pkd1tm1.1Pcha, polycystin 1, transient receptor poteintial channel interacting; targeted mutation 1.1, Peter Harris
Pkd1tm1Shh, polycystin 1, transient receptor poteintial channel interacting; targeted mutation 1, Shigeo Horie
Copyright: This image is from Hopp K, J Clin Invest 2012 Nov 1;122(11):4257-73 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:193544
Caption: Anosteopenia in Pkd1tm1.1Pcha/Pkd1tm1Shh mice characterized by a decrease in cortical and trabecular bone mass (details)
Represented Alleles:
Pkd1tm1.1Pcha, polycystin 1, transient receptor poteintial channel interacting; targeted mutation 1.1, Peter Harris
Pkd1tm1Shh, polycystin 1, transient receptor poteintial channel interacting; targeted mutation 1, Shigeo Horie
Copyright: This image is from Hopp K, J Clin Invest 2012 Nov 1;122(11):4257-73 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:193544

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
08/06/2019
MGI 6.14
The Jackson Laboratory