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Phenotype Images associated with this Gene
Symbol
Name
ID
Nkx2-5
NK2 homeobox 5
MGI:97350


4 phenotype image(s) for Nkx2-5 alleles
Showing image(s) 1 to 4

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Click on allele symbol for full phenotype details.

Caption: General and heart phenotype of Hspb7tm1.1Chen/Hspb7tm1.1Chen Nkx2-5tm1(cre)Rjs/Nkx2-5+ mice (details)
Represented Alleles:
Hspb7tm1.1Chen, heat shock protein family, member 7 (cardiovascular); targeted mutation 1.1, Ju Chen
Nkx2-5tm1(cre)Rjs, NK2 homeobox 5; targeted mutation 1, Robert J Schwartz
Copyright: This image is from Wu T, Proc Natl Acad Sci U S A 2017 Nov 7;114(45):11956-11961. Copyright 2017 National Academy of Sciences, U.S.A. J:256653
Caption: Abnormal heart development and coronary vasculogenesis in Nkx2-5tm1(cre)Rjs/Nkx2-5+ Zfpm2tm1Sho/Zfpm2tm2Sho mice (details)
Represented Alleles:
Nkx2-5tm1(cre)Rjs, NK2 homeobox 5; targeted mutation 1, Robert J Schwartz
Zfpm2tm1Sho, zinc finger protein, multitype 2; targeted mutation 1, Stuart Orkin
Zfpm2tm2Sho, zinc finger protein, multitype 2; targeted mutation 2, Stuart Orkin
Copyright: This image is from Zhou B, J Clin Invest 2009 Jun;119(6):1462-76 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:150452
Caption: Paucity of coronary vessels in Zfpm2tm1Sho/Zfpm2tm2Sho Nkx2-5tm1(cre)Rjs/Nkx2-5+ hearts (details)
Represented Alleles:
Nkx2-5tm1(cre)Rjs, NK2 homeobox 5; targeted mutation 1, Robert J Schwartz
Zfpm2tm1Sho, zinc finger protein, multitype 2; targeted mutation 1, Stuart Orkin
Zfpm2tm2Sho, zinc finger protein, multitype 2; targeted mutation 2, Stuart Orkin
Copyright: This image is from Zhou B, J Clin Invest 2009 Jun;119(6):1462-76 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:150452
Caption: Edema, peripheral hemorrhage, and reduced coronary plexus in Gata4tm1.1Wtp/Gata4tm1Sho Nkx2-5tm1(cre)Rjs/Nkx2-5+ embryos and enlarged dilated ventricles and increased fibrosis in Gata4tm1.1Wtp/Gata4tm1Sho Tg(Myh6-cre)2182Mds/0 hearts (details)
Represented Alleles:
Gata4tm1.1Wtp, GATA binding protein 4; targeted mutation 1.1, William T Pu
Gata4tm1Sho, GATA binding protein 4; targeted mutation 1, Stuart Orkin
Nkx2-5tm1(cre)Rjs, NK2 homeobox 5; targeted mutation 1, Robert J Schwartz
Tg(Myh6-cre)2182Mds, transgene insertion 2182, Michael D Schneider
Copyright: This image is from Zhou B, J Clin Invest 2009 Jun;119(6):1462-76 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:150452

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
08/06/2019
MGI 6.14
The Jackson Laboratory