Phenotype Images associated with this Gene

About Help FAQ

Phenotype Images associated with this Gene

Symbol
Name
ID

Kdr
kinase insert domain protein receptor
MGI:96683

Click on thumbnail to view full size image with links to phenotype annotations.
Click on allele symbol for full phenotype details.

	Caption: Defect in angioblast differentiation in Pten^tm1Hwu/Pten^tm1Hwu Kdr^tm1Jrt/Kdr⁺ Twist2^{tm1.1(cre)Dor}/Twist2⁺ mice (details) Represented Alleles: Kdr^tm1Jrt, kinase insert domain protein receptor; targeted mutation 1, Janet Rossant Pten^tm1Hwu, phosphatase and tensin homolog; targeted mutation 1, Hong Wu Twist2^{tm1.1(cre)Dor}, twist basic helix-loop-helix transcription factor 2; targeted mutation 1.1, David M Ornitz Copyright: This image is from Tiozzo C, J Clin Invest 2012 Nov 1;122(11):3862-72 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:192736
	Caption: Loss of trabeculations in the heart of E9.5 and E10.5 Angpt1^tm1.2Seq/Angpt1^tm1.2Seq Kdr^tm2.1Jrt/Kdr⁺ embryos (details) Represented Alleles: Angpt1^tm1.2Seq, angiopoietin 1; targeted mutation 1.2, Susan E Quaggin Kdr^tm2.1Jrt, kinase insert domain protein receptor; targeted mutation 2.1, Janet Rossant Copyright: This image is from Jeansson M, J Clin Invest 2011 Jun 1;121(6):2278-89 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:174022
	Caption: Angpt1^tm1.2Seq/Angpt1^tm1.2Seq Kdr^tm2.1Jrt/Kdr⁺ embryos are grwoth restricted at E10.5 and have disorganized vasculature (details) Represented Alleles: Angpt1^tm1.2Seq, angiopoietin 1; targeted mutation 1.2, Susan E Quaggin Kdr^tm2.1Jrt, kinase insert domain protein receptor; targeted mutation 2.1, Janet Rossant Copyright: This image is from Jeansson M, J Clin Invest 2011 Jun 1;121(6):2278-89 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:174022
	Caption: Impaired cardiac development in Angpt1^tm1.2Seq/Angpt1^tm1.2Seq Kdr^tm2.1Jrt/Kdr⁺ embryos (details) Represented Alleles: Angpt1^tm1.2Seq, angiopoietin 1; targeted mutation 1.2, Susan E Quaggin Kdr^tm2.1Jrt, kinase insert domain protein receptor; targeted mutation 2.1, Janet Rossant Copyright: This image is from Jeansson M, J Clin Invest 2011 Jun 1;121(6):2278-89 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:174022
	Caption: Suppression of of extraretinal vascular outgrowth in ischemic Kdr^tm1.1Jamb/Kdr^tm1Jrt Tg(CAG-cre/Esr1)1Egwa/0 retinas (details) Represented Alleles:* Kdr^tm1.1Jamb, kinase insert domain protein receptor; targeted mutation 1.1, Jayakrishna Ambati Kdr^tm1Jrt, kinase insert domain protein receptor; targeted mutation 1, Janet Rossant Tg(CAG-cre/Esr1)1Egwa, transgene insertion 1, Gyohei Egawa Copyright:* This image is from Fukushima Y, J Clin Invest 2011 May 2;121(5):1974-85 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:173943
	Caption: Intraretinal vascular regeneration is interrupted in ischemic Kdr^tm1.1Jamb/Kdr^tm1Jrt Tg(CAG-cre/Esr1)1Egwa/0 retinas (details) Represented Alleles:* Kdr^tm1.1Jamb, kinase insert domain protein receptor; targeted mutation 1.1, Jayakrishna Ambati Kdr^tm1Jrt, kinase insert domain protein receptor; targeted mutation 1, Janet Rossant Tg(CAG-cre/Esr1)1Egwa, transgene insertion 1, Gyohei Egawa Copyright:* This image is from Fukushima Y, J Clin Invest 2011 May 2;121(5):1974-85 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:173943
	Caption: Absence of blood cells and vasculature in E9.5-10.5 Kdr^orv/Kdr^orv embryos (details) Represented Alleles: Kdr^orv, kinase insert domain protein receptor; orvieto Copyright: This image is from Sandell LL, Genesis 2011 Apr;49(4):342-59, and is displayed with the permission of Wiley-Blackwell, who owns the Copyright. J:171522
	Caption: Abnormal pharyngeal arches in Kdr^orv/Kdr^orv embryos (details) Represented Alleles: Kdr^orv, kinase insert domain protein receptor; orvieto Copyright: This image is from Sandell LL, Genesis 2011 Apr;49(4):342-59, and is displayed with the permission of Wiley-Blackwell, who owns the Copyright. J:171522
	Caption: Neural crest cell formation and migration abnormalities in Kdr^orv/Kdr^orv embryos (details) Represented Alleles: Kdr^orv, kinase insert domain protein receptor; orvieto Copyright: This image is from Sandell LL, Genesis 2011 Apr;49(4):342-59, and is displayed with the permission of Wiley-Blackwell, who owns the Copyright. J:171522
	Caption: Agenesis or hypoplasia of neuronal differentiation in the midbrain and cranial ganglia of Kdr^orv/Kdr^orv embryos (details) Represented Alleles: Kdr^orv, kinase insert domain protein receptor; orvieto Copyright: This image is from Sandell LL, Genesis 2011 Apr;49(4):342-59, and is displayed with the permission of Wiley-Blackwell, who owns the Copyright. J:171522

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23