Phenotype Images associated with this Gene

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Phenotype Images associated with this Gene

Symbol
Name
ID

Edn2
endothelin 2
MGI:95284

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Click on allele symbol for full phenotype details.

	Caption: Decreased body weight in Edn2^tm1Ywa/Edn2^tm1Ywa mice (details) Represented Alleles: Edn2^tm1Ywa, endothelin 2; targeted mutation 1, Masashi Yanagisawa Copyright: This image is from Chang I, J Clin Invest 2013 Jun 3;123(6):2643-53 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:201436
	Caption: Impaired lung morphology in Edn2^tm1Ywa/Edn2^tm1Ywa mice and tamoxifen-treated Edn2^tm1.1Nat/Edn2^tm1.1Nat Tg(CAG-cre/Esr1)5Amc/0 mice (details) Represented Alleles:* Edn2^tm1.1Nat, endothelin 2; targeted mutation 1.1, Jeremy Nathans Edn2^tm1Ywa, endothelin 2; targeted mutation 1, Masashi Yanagisawa Tg(CAG-cre/Esr1)5Amc, transgene insertion 5, Andrew P McMahon Copyright:* This image is from Chang I, J Clin Invest 2013 Jun 3;123(6):2643-53 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:201436
	Caption: Reduced nuclei number in brown adipose tissue of cold-exposed Edn2^tm1Ywa/Edn2^tm1Ywa mice (details) Represented Alleles: Edn2^tm1Ywa, endothelin 2; targeted mutation 1, Masashi Yanagisawa Copyright: This image is from Chang I, J Clin Invest 2013 Jun 3;123(6):2643-53 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:201436
	Caption: Retinal vascular defects in Igs1^{tm11(CAG-Bgeo,-Edn2)Nat}/Igs1⁺ Tg(Six3-cre)69Frty/0 mice (details) Represented Alleles: Igs1^{tm11(CAG-Bgeo,-Edn2)Nat}, intergenic site 1; targeted mutation 11, Jeremy Nathans Tg(Six3-cre)69Frty, transgene insertion 69, Yasuhide Furuta Copyright: This image is from Rattner A, Proc Natl Acad Sci U S A 2013 Oct 1;110(40):E3830-E3839. Copyright 2013 National Academy of Sciences, U.S.A. J:201133
	Caption: Inhibition of vascular growth and production of excess tip cells in Igs1^{tm11(CAG-Bgeo,-Edn2)Nat}/Igs1⁺ Tg(Six3-cre)69Frty/0 retinas (details) Represented Alleles: Igs1^{tm11(CAG-Bgeo,-Edn2)Nat}, intergenic site 1; targeted mutation 11, Jeremy Nathans Tg(Six3-cre)69Frty, transgene insertion 69, Yasuhide Furuta Copyright: This image is from Rattner A, Proc Natl Acad Sci U S A 2013 Oct 1;110(40):E3830-E3839. Copyright 2013 National Academy of Sciences, U.S.A. J:201133
	Caption: In developing Igs1^{tm11(CAG-Bgeo,-Edn2)Nat}/Igs1⁺ Tg(Six3-cre)69Frty/0 retinas, large regions of the endothelial cell network are not perfused (details) Represented Alleles: Igs1^{tm11(CAG-Bgeo,-Edn2)Nat}, intergenic site 1; targeted mutation 11, Jeremy Nathans Tg(Six3-cre)69Frty, transgene insertion 69, Yasuhide Furuta Copyright: This image is from Rattner A, Proc Natl Acad Sci U S A 2013 Oct 1;110(40):E3830-E3839. Copyright 2013 National Academy of Sciences, U.S.A. J:201133
	Caption: Altered vascular development in Igs1^{tm11(CAG-Bgeo,-Edn2)Nat}/Igs1⁺ Tg(Six3-cre)69Frty/0 retinas (details) Represented Alleles: Igs1^{tm11(CAG-Bgeo,-Edn2)Nat}, intergenic site 1; targeted mutation 11, Jeremy Nathans Tg(Six3-cre)69Frty, transgene insertion 69, Yasuhide Furuta Copyright: This image is from Rattner A, Proc Natl Acad Sci U S A 2013 Oct 1;110(40):E3830-E3839. Copyright 2013 National Academy of Sciences, U.S.A. J:201133
	Caption: Interstitial tip cells in adult Igs1^{tm11(CAG-Bgeo,-Edn2)Nat}/Igs1⁺ Tg(Pdgfra-cre)1Clc/0 retinas (details) Represented Alleles: Igs1^{tm11(CAG-Bgeo,-Edn2)Nat}, intergenic site 1; targeted mutation 11, Jeremy Nathans Tg(Pdgfra-cre)1Clc, transgene insertion 1, Constance L Cepko Copyright: This image is from Rattner A, Proc Natl Acad Sci U S A 2013 Oct 1;110(40):E3830-E3839. Copyright 2013 National Academy of Sciences, U.S.A. J:201133
	Caption: Spatially localized Edn2 expression results in local inhibition of retinal vascular development in Igs1^{tm11(CAG-Bgeo,-Edn2)Nat}/Igs1⁺ Tg(Pax6-cre,GFP)2Pgr/0 mice (details) Represented Alleles: Igs1^{tm11(CAG-Bgeo,-Edn2)Nat}, intergenic site 1; targeted mutation 11, Jeremy Nathans Tg(Pax6-cre,GFP)2Pgr, transgene insertion 2, Peter Gruss Copyright: This image is from Rattner A, Proc Natl Acad Sci U S A 2013 Oct 1;110(40):E3830-E3839. Copyright 2013 National Academy of Sciences, U.S.A. J:201133
	Caption: Inhibition of vascular development and midgestational lethality in Igs1^{tm11(CAG-Bgeo,-Edn2)Nat}/Igs1⁺ Edil3^{Tg(Sox2-cre)1Amc}/0 embryos (details) Represented Alleles: Edil3^{Tg(Sox2-cre)1Amc}, EGF-like repeats and discoidin I-like domains 3; transgene insertion 1, Andrew P McMahon Igs1^{tm11(CAG-Bgeo,-Edn2)Nat}, intergenic site 1; targeted mutation 11, Jeremy Nathans Copyright: This image is from Rattner A, Proc Natl Acad Sci U S A 2013 Oct 1;110(40):E3830-E3839. Copyright 2013 National Academy of Sciences, U.S.A. J:201133

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