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Phenotype Images associated with this Gene
Symbol
Name
ID
Smad4
SMAD family member 4
MGI:894293


8 phenotype image(s) for Smad4 alleles
Showing image(s) 1 to 8

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Caption: Pancreatic fibrosis and acinar-to-ductal metaplasia in Tg(MtTGFA)Lmb/0 (MT-TGFalpha) and Smad4tm1.1Gsu/Smad4tm1.1Gsu Ptf1atm1.1(cre)Cvw/Ptf1a+ Tg(MtTGFA)Lmb/0 (STP) mice (details)
Represented Alleles:
Ptf1atm1.1(cre)Cvw, pancreas specific transcription factor, 1a; targeted mutation 1.1, Christopher VE Wright
Smad4tm1.1Gsu, SMAD family member 4; targeted mutation 1.1, Gloria H Su
Tg(MtTGFA)Lmb, transgene insertion, Glenn Merlino
Copyright: This image is from Garcia-Carracedo D, PLoS One 2015;10(3):e0120851, an open-access article distributed under the terms of the Creative Commons Attribution License. J:229184
Caption: Increased number of PanIN lesions in the Smad4tm1.1Gsu/Smad4tm1.1Gsu Ptf1atm1.1(cre)Cvw/Ptf1a+ Tg(MtTGFA)Lmb/0 (STP) mice compared to Tg(MtTGFA)Lmb/0 (MT-TGFalpha) mice (details)
Represented Alleles:
Ptf1atm1.1(cre)Cvw, pancreas specific transcription factor, 1a; targeted mutation 1.1, Christopher VE Wright
Smad4tm1.1Gsu, SMAD family member 4; targeted mutation 1.1, Gloria H Su
Tg(MtTGFA)Lmb, transgene insertion, Glenn Merlino
Copyright: This image is from Garcia-Carracedo D, PLoS One 2015;10(3):e0120851, an open-access article distributed under the terms of the Creative Commons Attribution License. J:229184
Caption: Enhanced pancreatic epithelial expasnion in Smad4tm1.1Gsu/Smad4tm1.1Gsu Ptf1atm1.1(cre)Cvw/Ptf1a+ Tg(MtTGFA)Lmb/0 mice compared to Tg(MtTGFA)Lmb/0 mice (details)
Represented Alleles:
Ptf1atm1.1(cre)Cvw, pancreas specific transcription factor, 1a; targeted mutation 1.1, Christopher VE Wright
Smad4tm1.1Gsu, SMAD family member 4; targeted mutation 1.1, Gloria H Su
Tg(MtTGFA)Lmb, transgene insertion, Glenn Merlino
Copyright: This image is from Garcia-Carracedo D, PLoS One 2015;10(3):e0120851, an open-access article distributed under the terms of the Creative Commons Attribution License. J:229184
Caption: Aggravated pancreatic fibrosis in Smad4tm1.1Gsu/Smad4tm1.1Gsu Ptf1atm1.1(cre)Cvw/Ptf1a+ Tg(MtTGFA)Lmb/0 mice compared to Tg(MtTGFA)Lmb/0 mice (details)
Represented Alleles:
Ptf1atm1.1(cre)Cvw, pancreas specific transcription factor, 1a; targeted mutation 1.1, Christopher VE Wright
Smad4tm1.1Gsu, SMAD family member 4; targeted mutation 1.1, Gloria H Su
Tg(MtTGFA)Lmb, transgene insertion, Glenn Merlino
Copyright: This image is from Garcia-Carracedo D, PLoS One 2015;10(3):e0120851, an open-access article distributed under the terms of the Creative Commons Attribution License. J:229184
Caption: Elevated Mucin-6 expression indicates pancreatitis in Smad4tm1.1Gsu/Smad4tm1.1Gsu Ptf1atm1.1(cre)Cvw/Ptf1a+ Tg(MtTGFA)Lmb/0 (STP) mice (details)
Represented Alleles:
Ptf1atm1.1(cre)Cvw, pancreas specific transcription factor, 1a; targeted mutation 1.1, Christopher VE Wright
Smad4tm1.1Gsu, SMAD family member 4; targeted mutation 1.1, Gloria H Su
Tg(MtTGFA)Lmb, transgene insertion, Glenn Merlino
Copyright: This image is from Garcia-Carracedo D, PLoS One 2015;10(3):e0120851, an open-access article distributed under the terms of the Creative Commons Attribution License. J:229184
Caption: Phenotypic analysis of the compound in cis Apctm2Rfo/Apc+ Smad4E6sad/Smad4+ mouse model (details)
Represented Alleles:
Apctm2Rfo, adenomatosis polyposis coli; targeted mutation 2, Riccardo Fodde
Smad4E6sad, SMAD family member 4; Exon 6 splice acceptor deletion
Copyright: This image is from Gaspar C, PLoS Genet 2009 Jul;5(7):e1000547, an open-access article distributed under the terms of the Creative Commons Attribution License. J:151494
Caption: Stomach and stomach sections of 11 month old wild type and Smad4m4Mag/+ mice. (details)
Represented Alleles:
Smad4m4Mag, SMAD family member 4; mutation 4, Terry Magnuson
Copyright: This image is from Chen Y, Mamm Genome 2006 Mar;17(3):211-9 and is displayed with the permission of Springer Science + Business Media, Inc., New York who owns the copyright. J:106440
Caption: Morphological and molecular analyses of Smad4tm1Cxd/Smad4tm1Cxd embryos (details)
Represented Alleles:
Smad4tm1Cxd, SMAD family member 4; targeted mutation 1, Chu-Xia Deng
Copyright: This image is from Yang X, Proc Natl Acad Sci U S A 1998 Mar 31;95(7):3667-72. Copyright 1998 National Academy of Sciences, U.S.A. J:46852

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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory