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Phenotype Images associated with this Gene
Symbol
Name
ID
Apc
adenomatosis polyposis coli
MGI:88039


20 phenotype image(s) for Apc alleles
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Caption: Enhanced intestinal tumorigenesis in ApcMin/Apc+ Mir10atm1.1Ahl/Mir10atm1.1Ahl mice (details)
Represented Alleles:
ApcMin, adenomatosis polyposis coli; multiple intestinal neoplasia
Mir10atm1.1Ahl, microRNA 10a; targeted mutation 1.1, Anders Lund
Copyright: This image is from Stadthagen G, PLoS Genet 2013 Oct;9(10):e1003913, an open-access article distributed under the terms of the Creative Commons Attribution License. J:205135
Caption: Rab25tm1Jrgo/Rab25tm1Jrgo ApcMin/Apc+ mice exhibit increased intestinal adenoma formation compared to ApcMin/Apc+ mice (details)
Represented Alleles:
ApcMin, adenomatosis polyposis coli; multiple intestinal neoplasia
Rab25tm1Jrgo, RAB25, member RAS oncogene family; targeted mutation 1, James R Goldenring
Copyright: This image is from Nam KT, J Clin Invest 2010 Mar;120(3):840-9 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:158733
Caption: Rab25tm1Jrgo/Rab25tm1Jrgo ApcMin/Apc+ mice exhibit increased colon adenoma formation compared to ApcMin/Apc+ mice (details)
Represented Alleles:
ApcMin, adenomatosis polyposis coli; multiple intestinal neoplasia
Rab25tm1Jrgo, RAB25, member RAS oncogene family; targeted mutation 1, James R Goldenring
Copyright: This image is from Nam KT, J Clin Invest 2010 Mar;120(3):840-9 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:158733
Caption: Mammary adenocarcinomas from Apctm2Rfo/Apc+ mice (details)
Represented Alleles:
Apctm2Rfo, adenomatosis polyposis coli; targeted mutation 2, Riccardo Fodde
Copyright: This image is from Gaspar C, PLoS Genet 2009 Jul;5(7):e1000547, an open-access article distributed under the terms of the Creative Commons Attribution License. J:151494
Caption: Mammary tumors and pulmonary metastases from Apctm2Rfo/Apc+ mice show typical mammary glandular architecture and squamous differentiation (details)
Represented Alleles:
Apctm2Rfo, adenomatosis polyposis coli; targeted mutation 2, Riccardo Fodde
Copyright: This image is from Gaspar C, PLoS Genet 2009 Jul;5(7):e1000547, an open-access article distributed under the terms of the Creative Commons Attribution License. J:151494
Caption: Phenotypic analysis of the compound in cis Apctm2Rfo/Apc+ Smad4E6sad/Smad4+ mouse model (details)
Represented Alleles:
Apctm2Rfo, adenomatosis polyposis coli; targeted mutation 2, Riccardo Fodde
Smad4E6sad, SMAD family member 4; Exon 6 splice acceptor deletion
Copyright: This image is from Gaspar C, PLoS Genet 2009 Jul;5(7):e1000547, an open-access article distributed under the terms of the Creative Commons Attribution License. J:151494
Caption: Skeletogenesis is severely impaired in Apctm1Rsmi/Apctm1Rsmi Tg(Col2a1-cre)1Rsjo/0 mice (details)
Represented Alleles:
Apctm1Rsmi, adenomatosis polyposis coli; targeted mutation 1, Ron Smits
Tg(Col2a1-cre)1Rsjo, transgene insertion 1, Randall S Johnson
Copyright: This image is from Miclea RL, BMC Dev Biol 2009;9():26, an open-access article, licensee BioMed Central Ltd. J:149225
Caption: Skeletal abnormalities in Apctm1Rsmi/Apctm1Rsmi Tg(Col2a1-cre)1Rsjo/0 mice (details)
Represented Alleles:
Apctm1Rsmi, adenomatosis polyposis coli; targeted mutation 1, Ron Smits
Tg(Col2a1-cre)1Rsjo, transgene insertion 1, Randall S Johnson
Copyright: This image is from Miclea RL, BMC Dev Biol 2009;9():26, an open-access article, licensee BioMed Central Ltd. J:149225
Caption: Abnormal axial skeleton formation in E12.5 Apctm1Rsmi/Apctm1Rsmi Tg(Col2a1-cre)1Rsjo/0 embryos (details)
Represented Alleles:
Apctm1Rsmi, adenomatosis polyposis coli; targeted mutation 1, Ron Smits
Tg(Col2a1-cre)1Rsjo, transgene insertion 1, Randall S Johnson
Copyright: This image is from Miclea RL, BMC Dev Biol 2009;9():26, an open-access article, licensee BioMed Central Ltd. J:149225
Caption: No chondrogenic and osteogenic differentiation in the developing Apctm1Rsmi/Apctm1Rsmi Tg(Col2a1-cre)1Rsjo/0 humerus (details)
Represented Alleles:
Apctm1Rsmi, adenomatosis polyposis coli; targeted mutation 1, Ron Smits
Tg(Col2a1-cre)1Rsjo, transgene insertion 1, Randall S Johnson
Copyright: This image is from Miclea RL, BMC Dev Biol 2009;9():26, an open-access article, licensee BioMed Central Ltd. J:149225

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory