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Phenotype Images associated with this Gene
Symbol
Name
ID 		b2b2025.2Clo
Mutant line 2025.2
MGI:5554525


13 phenotype image(s) for b2b2025.2Clo alleles
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Click on allele symbol for full phenotype details.

Caption: Mutant 2025-007-1 (E16.5) presents with malaligned great arteries, right aortic arch (RAA), and hypoplastic pulmonary artery (details)
Represented Alleles:
b2b2025.2Clo, Mutant line 2025.2; Bench to Bassinet Program (B2B/CVDC), mutation 2025, subline 2 Cecilia Lo
b2b2025Clo, Mutant line 2025; Bench to Bassinet Program (B2B/CVDC), mutation 2025 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: EFIC Summary (details)
Represented Alleles:
b2b2025.2Clo, Mutant line 2025.2; Bench to Bassinet Program (B2B/CVDC), mutation 2025, subline 2 Cecilia Lo
b2b2025Clo, Mutant line 2025; Bench to Bassinet Program (B2B/CVDC), mutation 2025 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Serial EFIC image stack in coronal plane of mutant 2025-007-1 (E16.5) shows DORV, AVSD, RAA, RV non-compaction, hypoplastic PA, aberrant left subclavian artery forming incomplete vascular ring
Click thumbnail to play movie. (details)
Represented Alleles:
b2b2025.2Clo, Mutant line 2025.2; Bench to Bassinet Program (B2B/CVDC), mutation 2025, subline 2 Cecilia Lo
b2b2025Clo, Mutant line 2025; Bench to Bassinet Program (B2B/CVDC), mutation 2025 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Mutant 2025-007-1 (E16.5) has micropthalmia of the right eye (details)
Represented Alleles:
b2b2025.2Clo, Mutant line 2025.2; Bench to Bassinet Program (B2B/CVDC), mutation 2025, subline 2 Cecilia Lo
b2b2025Clo, Mutant line 2025; Bench to Bassinet Program (B2B/CVDC), mutation 2025 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Mutant 2025-007-1 (E16.5) exhibits an abnormal patterning on the ventricles which is diagnosed as ventricular non-compaction by EFIC imaging (details)
Represented Alleles:
b2b2025.2Clo, Mutant line 2025.2; Bench to Bassinet Program (B2B/CVDC), mutation 2025, subline 2 Cecilia Lo
b2b2025Clo, Mutant line 2025; Bench to Bassinet Program (B2B/CVDC), mutation 2025 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Mutant 2025-007-2 (E16.5) exhibits malaligned great arteries shown to be double outlet right ventricle (DORV) by EFIC imaging (details)
Represented Alleles:
b2b2025.2Clo, Mutant line 2025.2; Bench to Bassinet Program (B2B/CVDC), mutation 2025, subline 2 Cecilia Lo
b2b2025Clo, Mutant line 2025; Bench to Bassinet Program (B2B/CVDC), mutation 2025 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: EFIC Summary (details)
Represented Alleles:
b2b2025.2Clo, Mutant line 2025.2; Bench to Bassinet Program (B2B/CVDC), mutation 2025, subline 2 Cecilia Lo
b2b2025Clo, Mutant line 2025; Bench to Bassinet Program (B2B/CVDC), mutation 2025 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Serial EFIC image stack in coronal plane of 2025-007-2 (E16.5) shows DORV, AVSD, spongy ventricles, aberrant right subclavian artery forming incomplete vascular ring
Click thumbnail to play movie. (details)
Represented Alleles:
b2b2025.2Clo, Mutant line 2025.2; Bench to Bassinet Program (B2B/CVDC), mutation 2025, subline 2 Cecilia Lo
b2b2025Clo, Mutant line 2025; Bench to Bassinet Program (B2B/CVDC), mutation 2025 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Color flow spectral Doppler imaging of mutant 2025-007-2 (E16.5) in the frontal view shows AO and PA originate from RV (details)
Represented Alleles:
b2b2025.2Clo, Mutant line 2025.2; Bench to Bassinet Program (B2B/CVDC), mutation 2025, subline 2 Cecilia Lo
b2b2025Clo, Mutant line 2025; Bench to Bassinet Program (B2B/CVDC), mutation 2025 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Color flow spectral Doppler imaging of mutant 2025-007-2 (E16.5) in the transverse view shows AVSD (details)
Represented Alleles:
b2b2025.2Clo, Mutant line 2025.2; Bench to Bassinet Program (B2B/CVDC), mutation 2025, subline 2 Cecilia Lo
b2b2025Clo, Mutant line 2025; Bench to Bassinet Program (B2B/CVDC), mutation 2025 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/16/2024
MGI 6.23 		The Jackson Laboratory