Phenotype Images associated with this Gene

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Phenotype Images associated with this Gene

Symbol
Name
ID

Mfn2
mitofusin 2
MGI:2442230

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Click on allele symbol for full phenotype details.

	Caption: Autophagosome accumulation in Mfn2^tm1.1Mzhe/Mfn2^tm1.1Mzhe Myl2^tm1(cre)Krc/Myl2⁺ hearts (details) Represented Alleles: Mfn2^tm1.1Mzhe, mitofusin 2; targeted mutation 1.1, Ming Zheng Myl2^tm1(cre)Krc, myosin, light polypeptide 2, regulatory, cardiac, slow; targeted mutation 1, Kenneth R Chien Copyright: This image is from Zhao T, J Biol Chem 2012 Jul 6;287(28):23615-25 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:188865
	Caption: Impaired lipid metabolism and accumulation of lipofuscin granules in Mfn2^tm1.1Mzhe/Mfn2^tm1.1Mzhe Myl2^tm1(cre)Krc/Myl2⁺ cardiomyocytes (details) Represented Alleles: Mfn2^tm1.1Mzhe, mitofusin 2; targeted mutation 1.1, Ming Zheng Myl2^tm1(cre)Krc, myosin, light polypeptide 2, regulatory, cardiac, slow; targeted mutation 1, Kenneth R Chien Copyright: This image is from Zhao T, J Biol Chem 2012 Jul 6;287(28):23615-25 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:188865
	Caption: Mfn2^tm1.1Mzhe/Mfn2^tm1.1Mzhe Myl2^tm1(cre)Krc/Myl2⁺ cardiomyocytes show a greater loss of mitochondrial membrane potential following ischemia-reperfusion (details) Represented Alleles: Mfn2^tm1.1Mzhe, mitofusin 2; targeted mutation 1.1, Ming Zheng Myl2^tm1(cre)Krc, myosin, light polypeptide 2, regulatory, cardiac, slow; targeted mutation 1, Kenneth R Chien Copyright: This image is from Zhao T, J Biol Chem 2012 Jul 6;287(28):23615-25 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:188865
	Caption: Enlarged mitochondria in Mfn2^tm1.1Mzhe/Mfn2^tm1.1Mzhe Myl2^tm1(cre)Krc/Myl2⁺ heart (details) Represented Alleles: Mfn2^tm1.1Mzhe, mitofusin 2; targeted mutation 1.1, Ming Zheng Myl2^tm1(cre)Krc, myosin, light polypeptide 2, regulatory, cardiac, slow; targeted mutation 1, Kenneth R Chien Copyright: This image is from Zhao T, J Biol Chem 2012 Jul 6;287(28):23615-25 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:188865
	Caption: Defective giant cell layer of Mfn2^tm1Dcc/Mfn2^tm1Dcc placenta (details) Represented Alleles: Mfn2^tm1Dcc, mitofusin 2; targeted mutation 1, David C Chan Copyright: This image is from Chen H, J Cell Biol 2003 Jan 21;160(2):189-200, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:81438

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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