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Phenotype Images associated with this Gene
Symbol
Name
ID
Mfn2
mitofusin 2
MGI:2442230


5 phenotype image(s) for Mfn2 alleles
Showing image(s) 1 to 5

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Click on allele symbol for full phenotype details.

Caption: Autophagosome accumulation in Mfn2tm1.1Mzhe/Mfn2tm1.1Mzhe Myl2tm1(cre)Krc/Myl2+ hearts (details)
Represented Alleles:
Mfn2tm1.1Mzhe, mitofusin 2; targeted mutation 1.1, Ming Zheng
Myl2tm1(cre)Krc, myosin, light polypeptide 2, regulatory, cardiac, slow; targeted mutation 1, Kenneth R Chien
Copyright: This image is from Zhao T, J Biol Chem 2012 Jul 6;287(28):23615-25 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:188865
Caption: Impaired lipid metabolism and accumulation of lipofuscin granules in Mfn2tm1.1Mzhe/Mfn2tm1.1Mzhe Myl2tm1(cre)Krc/Myl2+ cardiomyocytes (details)
Represented Alleles:
Mfn2tm1.1Mzhe, mitofusin 2; targeted mutation 1.1, Ming Zheng
Myl2tm1(cre)Krc, myosin, light polypeptide 2, regulatory, cardiac, slow; targeted mutation 1, Kenneth R Chien
Copyright: This image is from Zhao T, J Biol Chem 2012 Jul 6;287(28):23615-25 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:188865
Caption: Mfn2tm1.1Mzhe/Mfn2tm1.1Mzhe Myl2tm1(cre)Krc/Myl2+ cardiomyocytes show a greater loss of mitochondrial membrane potential following ischemia-reperfusion (details)
Represented Alleles:
Mfn2tm1.1Mzhe, mitofusin 2; targeted mutation 1.1, Ming Zheng
Myl2tm1(cre)Krc, myosin, light polypeptide 2, regulatory, cardiac, slow; targeted mutation 1, Kenneth R Chien
Copyright: This image is from Zhao T, J Biol Chem 2012 Jul 6;287(28):23615-25 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:188865
Caption: Enlarged mitochondria in Mfn2tm1.1Mzhe/Mfn2tm1.1Mzhe Myl2tm1(cre)Krc/Myl2+ heart (details)
Represented Alleles:
Mfn2tm1.1Mzhe, mitofusin 2; targeted mutation 1.1, Ming Zheng
Myl2tm1(cre)Krc, myosin, light polypeptide 2, regulatory, cardiac, slow; targeted mutation 1, Kenneth R Chien
Copyright: This image is from Zhao T, J Biol Chem 2012 Jul 6;287(28):23615-25 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:188865
Caption: Defective giant cell layer of Mfn2tm1Dcc/Mfn2tm1Dcc placenta (details)
Represented Alleles:
Mfn2tm1Dcc, mitofusin 2; targeted mutation 1, David C Chan
Copyright: This image is from Chen H, J Cell Biol 2003 Jan 21;160(2):189-200, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:81438

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory