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Phenotype Images associated with this Gene
Symbol
Name
ID
Ift140
intraflagellar transport 140
MGI:2146906


16 phenotype image(s) for Ift140 alleles
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Caption: Craniofacial and skeletal mutants: (A-D) Fras1bfb, (E-G) Ift140cauli, (H-J) knyn, and (K-M) Crklsnoop homozygotes (details)
Represented Alleles:
Crklsnoop, v-crk avian sarcoma virus CT10 oncogene homolog-like; snoopy
Fras1bfb, Fraser extracellular matrix complex subunit 1; blood filled blisters
Ift140cauli, intraflagellar transport 140; cauliflower
knyn, kanyon
Copyright: This image is from Caruana G, PLoS One 2013;8(3):e55429, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:199856
Caption: Mutant 1283-007-NA exhibits abnormal arrangement of the outflow tracts with the aorta anterior, RAA, and thickened ventricular wall. Sample is diagnosed with PTA and biventricular hypertrophy by EFIC imaging (details)
Represented Alleles:
Ift140b2b1283Clo, intraflagellar transport 140; Bench to Bassinet Program (B2B/CVDC), mutation 1283 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: EFIC Summary (details)
Represented Alleles:
Ift140b2b1283Clo, intraflagellar transport 140; Bench to Bassinet Program (B2B/CVDC), mutation 1283 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Serial 2D EFIC image stack in the coronal plane of 1283-007-NA reveals PTA (type A2), AVSD, RAA, and biventricular hypertrophy
Click thumbnail to play movie. (details)
Represented Alleles:
Ift140b2b1283Clo, intraflagellar transport 140; Bench to Bassinet Program (B2B/CVDC), mutation 1283 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Mutant 1283-007-NA presents with left kidney agenesis, hydronephrosis of the right kidney, and cystic kidney which is confirmed by histology (details)
Represented Alleles:
Ift140b2b1283Clo, intraflagellar transport 140; Bench to Bassinet Program (B2B/CVDC), mutation 1283 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Right kidney of mutant 1283-007-NA is hydronephrotic and has hydroureter. Some cysts are present (details)
Represented Alleles:
Ift140b2b1283Clo, intraflagellar transport 140; Bench to Bassinet Program (B2B/CVDC), mutation 1283 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Mutant 1283-003-2 (E16.5) presents with a cleft palate (details)
Represented Alleles:
Ift140b2b1283Clo, intraflagellar transport 140; Bench to Bassinet Program (B2B/CVDC), mutation 1283 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Mutant 1283-003-2 (E16.5) presents with left lung isomerism, normal outflow, and thickened ventricular wall which is diagnosed as biventricular hypertrophy by EFIC imaging (details)
Represented Alleles:
Ift140b2b1283Clo, intraflagellar transport 140; Bench to Bassinet Program (B2B/CVDC), mutation 1283 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Mutant 1283-003-2 (E16.5) shows heterotaxy with malrotated gut, left-sided stomach, midline pancreas, and asplenia (details)
Represented Alleles:
Ift140b2b1283Clo, intraflagellar transport 140; Bench to Bassinet Program (B2B/CVDC), mutation 1283 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: EFIC Summary (details)
Represented Alleles:
Ift140b2b1283Clo, intraflagellar transport 140; Bench to Bassinet Program (B2B/CVDC), mutation 1283 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/05/2019
MGI 6.14
The Jackson Laboratory