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Phenotype Images associated with this Gene
Symbol
Name
ID
Sirt2
sirtuin 2
MGI:1927664


4 phenotype image(s) for Sirt2 alleles
Showing image(s) 1 to 4

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Click on allele symbol for full phenotype details.

Caption: Sirt2tm1.1Auw/Sirt2tm1.1Auw Tg(Mpz-cre)26Mes/0 mice display hypomyelination (details)
Represented Alleles:
Sirt2tm1.1Auw, sirtuin 2; targeted mutation 1.1, Johan Auwerx
Tg(Mpz-cre)26Mes, transgene insertion 26, Albee Messing
Copyright: This image is from Beirowski B, Proc Natl Acad Sci U S A 2011 Oct 25;108(43):E952-61. Copyright 2011 National Academy of Sciences, U.S.A. J:177468
Caption: Delayed remyelination after nerve crush injury in Col1a1tm1(CAG-Sirt2)Jmi/Col1a1tm1(CAG-Sirt2)Jmi Tg(Mpz-cre)26Mes/0 mice (details)
Represented Alleles:
Col1a1tm1(CAG-Sirt2)Jmi, collagen, type I, alpha 1; targeted mutation 1, Jeffrey Milbrandt
Tg(Mpz-cre)26Mes, transgene insertion 26, Albee Messing
Copyright: This image is from Beirowski B, Proc Natl Acad Sci U S A 2011 Oct 25;108(43):E952-61. Copyright 2011 National Academy of Sciences, U.S.A. J:177468
Caption: Hypomyelination in Sirt2tm1.1Auw/Sirt2tm1.1Auw Tg(Mpz-cre)26Mes/0 mice (details)
Represented Alleles:
Sirt2tm1.1Auw, sirtuin 2; targeted mutation 1.1, Johan Auwerx
Tg(Mpz-cre)26Mes, transgene insertion 26, Albee Messing
Copyright: This image is from Beirowski B, Proc Natl Acad Sci U S A 2011 Oct 25;108(43):E952-61. Copyright 2011 National Academy of Sciences, U.S.A. J:177468
Caption: Abnormal myelin outfoldings in Sirt2tm1.1Auw/Sirt2tm1.1Auw Tg(Mpz-cre)26Mes/0 sciatic nerves (details)
Represented Alleles:
Sirt2tm1.1Auw, sirtuin 2; targeted mutation 1.1, Johan Auwerx
Tg(Mpz-cre)26Mes, transgene insertion 26, Albee Messing
Copyright: This image is from Beirowski B, Proc Natl Acad Sci U S A 2011 Oct 25;108(43):E952-61. Copyright 2011 National Academy of Sciences, U.S.A. J:177468

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory