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Phenotype Images associated with this Gene
Symbol
Name
ID
Slit3
slit guidance ligand 3
MGI:1315202


14 phenotype image(s) for Slit3 alleles
Showing image(s) 1 to 10
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Click on allele symbol for full phenotype details.

Caption: Mutant 2362-004-1 (E16.5) exhibits ectopia cordis, ventricular non-compaction, and gastroschisis with a body wall closure defect (details)
Represented Alleles:
b2b2362Clo, Mutant line 2362; Bench to Bassinet Program (B2B/CVDC), mutation 2362 Cecilia Lo
Slit3b2b2362.1Clo, slit guidance ligand 3; Bench to Bassinet Program (B2B/CVDC) mutation 2362, subline 1, Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Mutant 2362-004-1 (E16.5) with ectopia cortis exhibits DORV with aorta positioned anteriorly (Taussig Bing subtype DORV), which was confirmed by EFIC histology (details)
Represented Alleles:
b2b2362Clo, Mutant line 2362; Bench to Bassinet Program (B2B/CVDC), mutation 2362 Cecilia Lo
Slit3b2b2362.1Clo, slit guidance ligand 3; Bench to Bassinet Program (B2B/CVDC) mutation 2362, subline 1, Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: EFIC Summary (details)
Represented Alleles:
b2b2362Clo, Mutant line 2362; Bench to Bassinet Program (B2B/CVDC), mutation 2362 Cecilia Lo
Slit3b2b2362.1Clo, slit guidance ligand 3; Bench to Bassinet Program (B2B/CVDC) mutation 2362, subline 1, Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Serial 2D EFIC image stack in the coronal plane of 2362-004-1 (E16.5) reveals Taussig-Bing type DORV, AVSD, and ventricular non-compaction
Click thumbnail to play movie. (details)
Represented Alleles:
b2b2362Clo, Mutant line 2362; Bench to Bassinet Program (B2B/CVDC), mutation 2362 Cecilia Lo
Slit3b2b2362.1Clo, slit guidance ligand 3; Bench to Bassinet Program (B2B/CVDC) mutation 2362, subline 1, Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Ultrasound imaging of mutant 2362-004 (E16.5) in the sagittal view shows the heart out of the chest, suggesting ectopia cordis
Click thumbnail to play movie. (details)
Represented Alleles:
b2b2362Clo, Mutant line 2362; Bench to Bassinet Program (B2B/CVDC), mutation 2362 Cecilia Lo
Slit3b2b2362.1Clo, slit guidance ligand 3; Bench to Bassinet Program (B2B/CVDC) mutation 2362, subline 1, Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Mutant embryo at E16.5 show abnormal severely hypoplastic kidney. (details)
Represented Alleles:
b2b2362Clo, Mutant line 2362; Bench to Bassinet Program (B2B/CVDC), mutation 2362 Cecilia Lo
Slit3b2b2362.1Clo, slit guidance ligand 3; Bench to Bassinet Program (B2B/CVDC) mutation 2362, subline 1, Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Mutant 2362-004-2 (E16.5) was diagnosed as having DORV by fetal echocardiography, later confirmed by EFIC histology (details)
Represented Alleles:
b2b2362Clo, Mutant line 2362; Bench to Bassinet Program (B2B/CVDC), mutation 2362 Cecilia Lo
Slit3b2b2362.1Clo, slit guidance ligand 3; Bench to Bassinet Program (B2B/CVDC) mutation 2362, subline 1, Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: EFIC Summary (details)
Represented Alleles:
b2b2362Clo, Mutant line 2362; Bench to Bassinet Program (B2B/CVDC), mutation 2362 Cecilia Lo
Slit3b2b2362.1Clo, slit guidance ligand 3; Bench to Bassinet Program (B2B/CVDC) mutation 2362, subline 1, Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Serial 2D EFIC image stack in the coronal plane of 2362-004-2 (E16.5) reveals DORV and a subaortic VSD
Click thumbnail to play movie. (details)
Represented Alleles:
b2b2362Clo, Mutant line 2362; Bench to Bassinet Program (B2B/CVDC), mutation 2362 Cecilia Lo
Slit3b2b2362.1Clo, slit guidance ligand 3; Bench to Bassinet Program (B2B/CVDC) mutation 2362, subline 1, Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Mutant embryo (E16.5) has a few glomerular cysts. (details)
Represented Alleles:
b2b2362Clo, Mutant line 2362; Bench to Bassinet Program (B2B/CVDC), mutation 2362 Cecilia Lo
Slit3b2b2362.1Clo, slit guidance ligand 3; Bench to Bassinet Program (B2B/CVDC) mutation 2362, subline 1, Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory