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Phenotype Images associated with this Gene
presenilin 1

2 phenotype image(s) for Psen1 alleles
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Caption: Amyloid beta deposits in Apptm3.1Zhe/Apptm3.1Zhe Psen1tm1Mpm/Psen1tm1Mpm mice (details)
Represented Alleles:
Apptm3.1Zhe, amyloid beta (A4) precursor protein; targeted mutation 3.1, Hui Zheng
Psen1tm1Mpm, presenilin 1; targeted mutation 1, Mark P Mattson
Copyright: This image is from Li H, J Biol Chem 2010 Oct 1;285(40):30598-605 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:166379
Caption: Psen1tm1Bdes/Psen1tm1Bdes Psen2tm1Bdes/Psen2tm1Bdes embryos display severe growth retardation at E9.5 (details)
Represented Alleles:
Psen1tm1Bdes, presenilin 1; targeted mutation 1, Bart de Strooper
Psen2tm1Bdes, presenilin 2; targeted mutation 1, Bart de Strooper
Copyright: This image is from Herreman A, Proc Natl Acad Sci U S A 1999 Oct 12;96(21):11872-7. Copyright 1999 National Academy of Sciences, U.S.A. J:58118

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.08
The Jackson Laboratory