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Phenotype Images associated with this Gene
Symbol
Name
ID
Psen1
presenilin 1
MGI:1202717


5 phenotype image(s) for Psen1 alleles
Showing image(s) 1 to 5

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Click on allele symbol for full phenotype details.

Caption: Beta-amyloid plaques in Tg(APPswe,PSEN1dE9)85Dbo/0 mice and neurofibrillary tangles in Mapttm1(EGFP)Klt/Mapttm1(EGFP)Klt Tg(MAPT)8cPdav/0 mice (details)
Represented Alleles:
Mapttm1(EGFP)Klt, microtubule-associated protein tau; targeted mutation 1, Kerry Lee Tucker
Tg(APPswe,PSEN1dE9)85Dbo, transgene insertion 85, David R Borchelt
Tg(MAPT)8cPdav, transgene insertion 8c, Peter Davies
Copyright: This image is from Phillips M, PLoS One 2011;6(5):e19567, an open-access article distributed under the terms of the Creative Commons Attribution License. J:172426
Caption: Amyloid beta deposits in Apptm3.1Zhe/Apptm3.1Zhe Psen1tm1Mpm/Psen1tm1Mpm mice (details)
Represented Alleles:
Apptm3.1Zhe, amyloid beta (A4) precursor protein; targeted mutation 3.1, Hui Zheng
Psen1tm1Mpm, presenilin 1; targeted mutation 1, Mark P Mattson
Copyright: This image is from Li H, J Biol Chem 2010 Oct 1;285(40):30598-605 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:166379
Caption: Amyloid pathology and glial inflammation in hemizygous and homozygous Tg(Thy1-PSEN1*M146V,-APP*Swe)10Arte mouse brain (details)
Represented Alleles:
Tg(Thy1-PSEN1*M146V,-APP*Swe)10Arte, transgene insertion 10, TaconicArtemis
Copyright: This image is from Willuweit A, PLoS One 2009;4(11):e7931, an open-access article distributed under the terms of the Creative Commons Attribution License. J:155410
Caption: Onset and development of plaques in Tg(Thy1-PSEN1*M146V,-APP*Swe)10Arte/Tg(Thy1-PSEN1*M146V,-APP*Swe)10Arte mice (details)
Represented Alleles:
Tg(Thy1-PSEN1*M146V,-APP*Swe)10Arte, transgene insertion 10, TaconicArtemis
Copyright: This image is from Willuweit A, PLoS One 2009;4(11):e7931, an open-access article distributed under the terms of the Creative Commons Attribution License. J:155410
Caption: Psen1tm1Bdes/Psen1tm1Bdes Psen2tm1Bdes/Psen2tm1Bdes embryos display severe growth retardation at E9.5 (details)
Represented Alleles:
Psen1tm1Bdes, presenilin 1; targeted mutation 1, Bart de Strooper
Psen2tm1Bdes, presenilin 2; targeted mutation 1, Bart de Strooper
Copyright: This image is from Herreman A, Proc Natl Acad Sci U S A 1999 Oct 12;96(21):11872-7. Copyright 1999 National Academy of Sciences, U.S.A. J:58118

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/17/2017
MGI 6.10
The Jackson Laboratory