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Phenotype Images associated with this Gene
Symbol
Name
ID
Med1
mediator complex subunit 1
MGI:1100846


10 phenotype image(s) for Med1 alleles
Showing image(s) 1 to 10

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Click on allele symbol for full phenotype details.

Caption: Enlarged, flaccid and flabby hearts in Med1tm2Jkr/Med1tm2Jkr Tg(Myh6-cre)2182Mds/0 mice by E25. (details)
Represented Alleles:
Med1tm2Jkr, mediator complex subunit 1; targeted mutation 2, Janardan K Reddy
Copyright: This image is from Jia Y, PLoS One 2016;11(8):e0160755, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:243730
Caption: Heart sections of Med1tm2Jkr/Med1tm2Jkr Tg(Myh6-cre)2182Mds/0 heart reveal thinning of ventricular walls and dilation of chambers. (details)
Represented Alleles:
Med1tm2Jkr, mediator complex subunit 1; targeted mutation 2, Janardan K Reddy
Copyright: This image is from Jia Y, PLoS One 2016;11(8):e0160755, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:243730
Caption: Cardiac fibrosis, increased cardiomyocyte apoptosis and mitochondrial damage in Med1tm2Jkr/Med1tm2Jkr Tg(Myh6-cre)2182Mds/0 mouse heart (details)
Represented Alleles:
Med1tm2Jkr, mediator complex subunit 1; targeted mutation 2, Janardan K Reddy
Tg(Myh6-cre)2182Mds, transgene insertion 2182, Michael D Schneider
Copyright: This image is from Jia Y, PLoS One 2016;11(8):e0160755, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:243730
Caption: The Med1tm2Jkr/Med1tm2Jkr A1cfTg(Myh6-cre/Esr1*)1Jmk/A1cf+ mouse heart is flaccid and flabby after tamoxifen induction. (details)
Represented Alleles:
A1cfTg(Myh6-cre/Esr1*)1Jmk, APOBEC1 complementation factor; transgene insertion 1, Jeffery D Molkentin
Med1tm2Jkr, mediator complex subunit 1; targeted mutation 2, Janardan K Reddy
Copyright: This image is from Jia Y, PLoS One 2016;11(8):e0160755, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:243730
Caption: Cardiac fibrosis in Med1tm2Jkr/Med1tm2Jkr A1cfTg(Myh6-cre/Esr1*)1Jmk/A1cf+ mouse heart (details)
Represented Alleles:
A1cfTg(Myh6-cre/Esr1*)1Jmk, APOBEC1 complementation factor; transgene insertion 1, Jeffery D Molkentin
Med1tm2Jkr, mediator complex subunit 1; targeted mutation 2, Janardan K Reddy
Tg(Myh6-cre)2182Mds, transgene insertion 2182, Michael D Schneider
Copyright: This image is from Jia Y, PLoS One 2016;11(8):e0160755, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:243730
Caption: Cardiovascular development defects in Med1tm1Jkr/Med1tm1Jkr embryos (details)
Represented Alleles:
Med1tm1Jkr, mediator complex subunit 1; targeted mutation 1, Janardan K Reddy
Copyright: This image is from Crawford SE, J Biol Chem 2002 Feb 1;277(5):3585-92 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:74328
Caption: Defective angiogenesis in Med1tm1Jkr/Med1tm1Jkr embryos (details)
Represented Alleles:
Med1tm1Jkr, mediator complex subunit 1; targeted mutation 1, Janardan K Reddy
Copyright: This image is from Crawford SE, J Biol Chem 2002 Feb 1;277(5):3585-92 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:74328
Caption: Developmental eye abnormalities in Med1tm1Jkr/Med1tm1Jkr embryos (details)
Represented Alleles:
Med1tm1Jkr, mediator complex subunit 1; targeted mutation 1, Janardan K Reddy
Copyright: This image is from Crawford SE, J Biol Chem 2002 Feb 1;277(5):3585-92 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:74328
Caption: Liver of Med1tm1Jkr/Med1tm1Jkr embryos lacks mature megakaryocytes (details)
Represented Alleles:
Med1tm1Jkr, mediator complex subunit 1; targeted mutation 1, Janardan K Reddy
Copyright: This image is from Crawford SE, J Biol Chem 2002 Feb 1;277(5):3585-92 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:74328
Caption: Histological and ultrastructural alterations in Med1tm1Jkr/Med1tm1Jkr placenta (details)
Represented Alleles:
Med1tm1Jkr, mediator complex subunit 1; targeted mutation 1, Janardan K Reddy
Copyright: This image is from Zhu Y, J Biol Chem 2000 May 19;275(20):14779-82 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:62272

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/11/2020
MGI 6.14
The Jackson Laboratory