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Symbol Name ID |
Bmpr2
bone morphogenetic protein receptor type 2 MGI:1095407 |
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Caption: Mutant 2556-004-1 (E16.5) exhibits parallel outflow tracts and ventricles appear thin which is diagnosed as PTA (Type A4) and ventricular non-copmaction by EFIC imaging and the heart is malrotated further to the left
(details)
Represented Alleles:
Bmpr2b2b2556Clo,
bone morphogenetic protein receptor type 2; Bench to Bassinet Program (B2B/CVDC) mutation 2556, Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: EFIC Summary
(details)
Represented Alleles:
Bmpr2b2b2556Clo,
bone morphogenetic protein receptor type 2; Bench to Bassinet Program (B2B/CVDC) mutation 2556, Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: Serial 2D EFIC image stack in the coronal plane of 2556-004-1 (E16.5) reveals PTA (Type A4), no OFT valves, AVSD, and ventricular myocardial non-compaction
Click thumbnail to play movie. (details) Represented Alleles:
Bmpr2b2b2556Clo,
bone morphogenetic protein receptor type 2; Bench to Bassinet Program (B2B/CVDC) mutation 2556, Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: Color flow spectral Doppler imaging of mutant 2556-004-1 (E15.5) in the sagittal view shows only one thick great artery can be detected originating from the heart and severe regurgitation. These together suggest PTA.
Click thumbnail to play movie. (details) Represented Alleles:
Bmpr2b2b2556Clo,
bone morphogenetic protein receptor type 2; Bench to Bassinet Program (B2B/CVDC) mutation 2556, Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: Mutant 2556-004-1 (E16.5) presents with hydronephrosis
(details)
Represented Alleles:
Bmpr2b2b2556Clo,
bone morphogenetic protein receptor type 2; Bench to Bassinet Program (B2B/CVDC) mutation 2556, Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: Mutant 2556-004-6 (E16.5) shows an enlarged pulmonary, the heart is slightly malrotated to the left, and RV appears to have a thin wall which is diagnosed as incomplete separation of the outflow tracts and ventricular non-compaction by EFIC imaging
(details)
Represented Alleles:
Bmpr2b2b2556Clo,
bone morphogenetic protein receptor type 2; Bench to Bassinet Program (B2B/CVDC) mutation 2556, Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: EFIC Summary
(details)
Represented Alleles:
Bmpr2b2b2556Clo,
bone morphogenetic protein receptor type 2; Bench to Bassinet Program (B2B/CVDC) mutation 2556, Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: Serial 2D EFIC image stack in the coronal plane of 2556-004-6 (E16.5) reveals incomplete great artery septation at proximal region, ventricular septation, no PA valves, PDA, large interventricular foramen, and ventricular myocardial non-compaction
Click thumbnail to play movie. (details) Represented Alleles:
Bmpr2b2b2556Clo,
bone morphogenetic protein receptor type 2; Bench to Bassinet Program (B2B/CVDC) mutation 2556, Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: Mutant 2556-004-6 (16.5) presents with hydronephrosis
(details)
Represented Alleles:
Bmpr2b2b2556Clo,
bone morphogenetic protein receptor type 2; Bench to Bassinet Program (B2B/CVDC) mutation 2556, Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/16/2024 MGI 6.23 |
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