Symbol Name ID

Fen1 flap structure specific endonuclease 1 MGI:102779

4 phenotype image(s) for Fen1 alleles Showing image(s) 1 to 4

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Click on allele symbol for full phenotype details.

	Caption: (a) Accumulation of apoptotic nuclei in Fen1tm3.1Bhsh/Fen1tm3.1Bhsh tissues (details) Represented Alleles: Fen1tm3.1Bhsh, flap structure specific endonuclease 1; targeted mutation 3.1, Binghui Shen Copyright: This image is from Zheng L, Nat Med 2007 Jul;13(7):812-9 and is displayed with the permission of The Nature Publishing Group who owns the Copyright. J:231218
	Caption: Deposition of IgG immune complex onto the glomeruli and capillary walls of the kidneys and onto cells in the lungs of Fen1tm3.1Bhsh/Fen1tm3.1Bhsh mice (details) Represented Alleles: Fen1tm3.1Bhsh, flap structure specific endonuclease 1; targeted mutation 3.1, Binghui Shen Copyright: This image is from Zheng L, Nat Med 2007 Jul;13(7):812-9 and is displayed with the permission of The Nature Publishing Group who owns the Copyright. J:231218
	Caption: Fen1tm3.1Bhsh/Fen1tm3.1Bhsh mice are highly susceptible to cancers as a result of their mutator phenotype and chronic inflammation (details) Represented Alleles: Fen1tm3.1Bhsh, flap structure specific endonuclease 1; targeted mutation 3.1, Binghui Shen Copyright: This image is from Zheng L, Nat Med 2007 Jul;13(7):812-9 and is displayed with the permission of The Nature Publishing Group who owns the Copyright. J:231218
	Caption: Fen1tm3.1Bhsh/Fen1tm3.1Bhsh mice develop subcutaneous inflammation, lymphoproliferative disorder, and extramedular hematopoiesis (details) Represented Alleles: Fen1tm3.1Bhsh, flap structure specific endonuclease 1; targeted mutation 3.1, Binghui Shen Copyright: This image is from Zheng L, Nat Med 2007 Jul;13(7):812-9 and is displayed with the permission of The Nature Publishing Group who owns the Copyright. J:231218