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Phenotype Images associated with this Allele
Nomenclature
Symbol: Pdcd6iptm1.2Adz
Name: programmed cell death 6 interacting protein; targeted mutation 1.2, Alessandra d'Azzo
MGI ID: MGI:5824749
Synonyms: Alix-
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Smaller body size of Pdcd6iptm1.2Adz/Pdcd6iptm1.2Adz micePdcd6iptm1.2Adz/Pdcd6iptm1.2Adzeither: (involves: 129S1/Sv) or (involves: 129S1/Sv * C57BL/6)
Pdcd6iptm1.2Adz/Pdcd6iptm1.2Adz mice develop bilateral hydrocephalusPdcd6iptm1.2Adz/Pdcd6iptm1.2Adzeither: (involves: 129S1/Sv) or (involves: 129S1/Sv * C57BL/6)
Abnormal cell architecture and apical junctional complex in the Pdcd6iptm1.2Adz/Pdcd6iptm1.2Adz choroid plexusPdcd6iptm1.2Adz/Pdcd6iptm1.2Adzeither: (involves: 129S1/Sv) or (involves: 129S1/Sv * C57BL/6)
Motile cilia of lateral wall in Pdcd6iptm1.2Adz/Pdcd6iptm1.2Adz brain show defective orientationPdcd6iptm1.2Adz/Pdcd6iptm1.2Adzeither: (involves: 129S1/Sv) or (involves: 129S1/Sv * C57BL/6)
Pdcd6iptm1.2Adz/Pdcd6iptm1.2Adz epithelia display apoptotic cell extrusionPdcd6iptm1.2Adz/Pdcd6iptm1.2Adzeither: (involves: 129S1/Sv) or (involves: 129S1/Sv * C57BL/6)
The epithelial barrier of the choroid plexus is compromised in Pdcd6iptm1.2Adz/Pdcd6iptm1.2Adz micePdcd6iptm1.2Adz/Pdcd6iptm1.2Adzeither: (involves: 129S1/Sv) or (involves: 129S1/Sv * C57BL/6)
Abnormal blebbing of microvilli and mislocalization of basal bodies in Pdcd6iptm1.2Adz/Pdcd6iptm1.2Adz choroid plexusPdcd6iptm1.2Adz/Pdcd6iptm1.2Adzeither: (involves: 129S1/Sv) or (involves: 129S1/Sv * C57BL/6)
Abnormal sizes of ependymal cells and positioning of the basal bodies in Pdcd6iptm1.2Adz/Pdcd6iptm1.2Adz lateral wallPdcd6iptm1.2Adz/Pdcd6iptm1.2Adzeither: (involves: 129S1/Sv) or (involves: 129S1/Sv * C57BL/6)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
03/03/2020
MGI 6.15
The Jackson Laboratory