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Phenotype Images associated with this Allele
Nomenclature
Symbol: Myo5btm1.1Cle
Name: myosin VB; targeted mutation 1.1, Hans Clevers
MGI ID: MGI:5790962
Synonyms: Myo5bfl
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Microvillus inclusion disease phenotype in Myo5btm1.1Cle/Myo5btm1.1Cle Tg(Vil1-cre/ERT2)23Syr/0 miceMyo5btm1.1Cle/Myo5btm1.1Cle
Tg(Vil1-cre/ERT2)23Syr/0		involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6 * DBA/2
Lower villus cells are the first cells affected in Myo5btm1.1Cle/Myo5btm1.1Cle/ Tg(Vil1-cre/ERT2)23Syr/0 mice, showing accumulation of vesicles and widened intercellular spacesMyo5btm1.1Cle/Myo5btm1.1Cle
Tg(Vil1-cre/ERT2)23Syr/0		involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6 * DBA/2
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory