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Phenotype Images associated with this Allele
Nomenclature
Symbol: Plxnd1b2b3150Clo
Name: plexin D1; Bench to Bassinet Program (B2B/CVDC), mutation 3150 Cecilia Lo
MGI ID: MGI:5648017
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Mutant 3150-003-2 (E15.5) exhibits a hypoplastic and malpositioned.Plxnd1b2b3150Clo/Plxnd1b2b3150CloC57BL/6J-Plxnd1b2b3150Clo
Mutant 3150-003-2 (E15.5) presents with only one outflow tract which is diagnosed as PTA (Type 2) by EFIC imaging.Plxnd1b2b3150Clo/Plxnd1b2b3150CloC57BL/6J-Plxnd1b2b3150Clo
EFIC SummaryPlxnd1b2b3150Clo/Plxnd1b2b3150CloC57BL/6J-Plxnd1b2b3150Clo
Serial 2D EFIC image stack in the coronal plane of mutant 3150-003-2 (E15.5) reveals PTA (Type 2), AVSD, RAA, and aberrant left subclavian artery forming incomplete vascular ring.
Click thumbnail to play movie.		Plxnd1b2b3150Clo/Plxnd1b2b3150CloC57BL/6J-Plxnd1b2b3150Clo
Mutant 3150-003-2 (E15.5) exhibits right kidney agenesis and a hypoplastic left kidney.Plxnd1b2b3150Clo/Plxnd1b2b3150CloC57BL/6J-Plxnd1b2b3150Clo
Mutant 3150-003-1 (E15.5) exhibits only one outflow tract which is diagnosed as PTA (type 2) by EFIC imaging.Plxnd1b2b3150Clo/Plxnd1b2b3150CloC57BL/6J-Plxnd1b2b3150Clo
EFIC SummaryPlxnd1b2b3150Clo/Plxnd1b2b3150CloC57BL/6J-Plxnd1b2b3150Clo
Serial 2D EFIC image stack in the coronal plane of mutant 3150-003-1 (E15.5) reveals PTA (Type 2), AVSD, RAA, common atrium, mVSD, and aberrant left subclavian artery forming incomplete vascular ring.
Click thumbnail to play movie.		Plxnd1b2b3150Clo/Plxnd1b2b3150CloC57BL/6J-Plxnd1b2b3150Clo
Mutant 3150-003-1 (E15.5) has micrognathia, a short snout, petechiae, and hydropsPlxnd1b2b3150Clo/Plxnd1b2b3150CloC57BL/6J-Plxnd1b2b3150Clo
Mutant 3150-003-1 (E15.5) exhibits a cleft palate.Plxnd1b2b3150Clo/Plxnd1b2b3150CloC57BL/6J-Plxnd1b2b3150Clo
Mutant 3150-003-1 (E15.5) presents with bilateral kidney agenesis.Plxnd1b2b3150Clo/Plxnd1b2b3150CloC57BL/6J-Plxnd1b2b3150Clo
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/16/2024
MGI 6.23 		The Jackson Laboratory