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Phenotype Images associated with this Allele
Nomenclature
Symbol: Flnbtm1Vshn
Name: filamin, beta; targeted mutation 1, Volney Sheen
MGI ID: MGI:5620800
Synonyms: Flnb-
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Premature differentiation within the prehypertrophic zone in the long bone growth plates of Flnbtm1Vshn/Flnbtm1Vshn miceFlnbtm1Vshn/Flnbtm1Vshninvolves: 129S6/SvEvTac * C57BL/6
Flnbtm1Vshn/Flnbtm1Vshn mouse chondrocytes display decreased proliferation at postnatal agesFlnbtm1Vshn/Flnbtm1Vshninvolves: 129S6/SvEvTac * C57BL/6
Increased proliferating chondrocytes remaining in G1/G0 phase in Flnbtm1Vshn/Flnbtm1Vshn miceFlnbtm1Vshn/Flnbtm1Vshninvolves: 129S6/SvEvTac * C57BL/6
Flnbtm1Vshn/Flnbtm1Vshn mice display skeletal shortening and abnormalities in the growth plates of the appendicular bonesFlnbtm1Vshn/Flnbtm1Vshninvolves: 129S6/SvEvTac * C57BL/6
Flnbtm1Vshn/Flnbtm1Vshn mice display reduced hypertrophic to proliferative zone ratio in the growth plates of the appendicular bonesFlnbtm1Vshn/Flnbtm1Vshninvolves: 129S6/SvEvTac * C57BL/6
Increased differentiation in the long bone in Flnbtm1Vshn/Flnbtm1Vshn miceFlnbtm1Vshn/Flnbtm1Vshninvolves: 129S6/SvEvTac * C57BL/6

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/12/2022
MGI 6.17
The Jackson Laboratory