Phenotype Images associated with this Allele

Nomenclature

Symbol:	b2b2696Clo
Name:	Mutant line 2696; Bench to Bassinet Program (B2B/CVDC), mutation 2696 Cecilia Lo
MGI ID:	MGI:5620185

Images for
Allele

Click images for details

Image	Caption	Genotypes involving this allele
		Allelic Composition	Genetic Background
	Mutant (E14.5) shows dextrocardia with abnormal outflow tract arrangement with DORV as seen by ECM hisopathology.	b2b2696Clo/b2b2696Clo	C57BL/6J-b2b2696Clo
		b2b2696.1Clo/b2b2696.1Clo	C57BL/6J-b2b2696.1Clo
	EFIC Summary	b2b2696Clo/b2b2696Clo	C57BL/6J-b2b2696Clo
		b2b2696.1Clo/b2b2696.1Clo	C57BL/6J-b2b2696.1Clo
	Serial 2D ECM image stack of (ED14.5) in the coronal plane reveals dextracardia {A,D,D} with DORV, AVSD, muscular VSD, right atrial isomerism with absent coronary sinus, intracardiac TAPVR, dual IVC, left aortic arch, delayed myocardial compaction (or myocardial non-compaction), and left lung isomerism. Click thumbnail to play movie.	b2b2696Clo/b2b2696Clo	C57BL/6J-b2b2696Clo
		b2b2696.1Clo/b2b2696.1Clo	C57BL/6J-b2b2696.1Clo
	Mutant (E14.5) presents with a right-sided pancreas, asplenia, left-sided stomach and gut malrotation.	b2b2696Clo/b2b2696Clo	C57BL/6J-b2b2696Clo
		b2b2696.1Clo/b2b2696.1Clo	C57BL/6J-b2b2696.1Clo
	Mutant exhibits a right aortic arch which was confirmed by ECM imaging.	b2b2696Clo/b2b2696Clo	C57BL/6J-b2b2696Clo
		b2b2696.2Clo/b2b2696.2Clo	C57BL/6J-b2b2696.2Clo
	EFIC Summary	b2b2696Clo/b2b2696Clo	C57BL/6J-b2b2696Clo
		b2b2696.2Clo/b2b2696.2Clo	C57BL/6J-b2b2696.2Clo
	Serial 2D ECM image stack in the coronal plane of mutant reveals right aortic arch, coronary artery fistula, and aberrant left subclavian artery forming incomplete vascular ring. Click thumbnail to play movie.	b2b2696Clo/b2b2696Clo	C57BL/6J-b2b2696Clo
		b2b2696.2Clo/b2b2696.2Clo	C57BL/6J-b2b2696.2Clo
	Mutant exhibits craniofacial defects which include craniofacial hypoplasia, severe micrognathia/agnathia, bilateral anopthalmia, and low-set ears.	b2b2696Clo/b2b2696Clo	C57BL/6J-b2b2696Clo
		b2b2696.2Clo/b2b2696.2Clo	C57BL/6J-b2b2696.2Clo
	Mutant presents with apparent left ventricular hypertrophy which was confirmed by ECM histopatholog	b2b2696Clo/b2b2696Clo	C57BL/6J-b2b2696Clo
		b2b2696.2Clo/b2b2696.2Clo	C57BL/6J-b2b2696.2Clo
	EFIC Summary	b2b2696Clo/b2b2696Clo	C57BL/6J-b2b2696Clo
		b2b2696.2Clo/b2b2696.2Clo	C57BL/6J-b2b2696.2Clo
	Serial 2D ECM image stack in the coronal plane of mutant reveals atrioventricular septal defect (AVSD) with apparent left ventricular hypertrophy. Click thumbnail to play movie.	b2b2696Clo/b2b2696Clo	C57BL/6J-b2b2696Clo
		b2b2696.2Clo/b2b2696.2Clo	C57BL/6J-b2b2696.2Clo
	Mutant presents with right sided anopthalmia.	b2b2696Clo/b2b2696Clo	C57BL/6J-b2b2696Clo
		b2b2696.2Clo/b2b2696.2Clo	C57BL/6J-b2b2696.2Clo
	Mutant exhibits cryptophthalmos, short snout, micrognathia, and low-set ears.	b2b2696Clo/b2b2696Clo	C57BL/6J-b2b2696Clo
		b2b2696.2Clo/b2b2696.2Clo	C57BL/6J-b2b2696.2Clo
	Mutant presents with unilateral anopathalmia and left sided cryptophthalmos.	b2b2696Clo/b2b2696Clo	C57BL/6J-b2b2696Clo
		b2b2696.2Clo/b2b2696.2Clo	C57BL/6J-b2b2696.2Clo
	Mutant presents with a midline facial cleft.	b2b2696Clo/b2b2696Clo	C57BL/6J-b2b2696Clo
		b2b2696.2Clo/b2b2696.2Clo	C57BL/6J-b2b2696.2Clo

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