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Phenotype Images associated with this Allele
Nomenclature
Symbol: b2b2025.2Clo
Name: Mutant line 2025.2; Bench to Bassinet Program (B2B/CVDC), mutation 2025, subline 2 Cecilia Lo
MGI ID: MGI:5554445
Images for
Allele
Click images for details
Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Mutant 2025-007-1 (E16.5) presents with malaligned great arteries, right aortic arch (RAA), and hypoplastic pulmonary arteryb2b2025Clo/b2b2025CloC57BL/6J-b2b2025Clo
b2b2025.2Clo/b2b2025.2CloC57BL/6J-b2b2025.2Clo
EFIC Summaryb2b2025Clo/b2b2025CloC57BL/6J-b2b2025Clo
b2b2025.2Clo/b2b2025.2CloC57BL/6J-b2b2025.2Clo
Serial EFIC image stack in coronal plane of mutant 2025-007-1 (E16.5) shows DORV, AVSD, RAA, RV non-compaction, hypoplastic PA, aberrant left subclavian artery forming incomplete vascular ring
Click thumbnail to play movie.		b2b2025Clo/b2b2025CloC57BL/6J-b2b2025Clo
b2b2025.2Clo/b2b2025.2CloC57BL/6J-b2b2025.2Clo
Mutant 2025-007-1 (E16.5) has micropthalmia of the right eyeb2b2025Clo/b2b2025CloC57BL/6J-b2b2025Clo
b2b2025.2Clo/b2b2025.2CloC57BL/6J-b2b2025.2Clo
Mutant 2025-007-1 (E16.5) exhibits an abnormal patterning on the ventricles which is diagnosed as ventricular non-compaction by EFIC imagingb2b2025Clo/b2b2025CloC57BL/6J-b2b2025Clo
b2b2025.2Clo/b2b2025.2CloC57BL/6J-b2b2025.2Clo
Mutant 2025-007-2 (E16.5) exhibits malaligned great arteries shown to be double outlet right ventricle (DORV) by EFIC imagingb2b2025Clo/b2b2025CloC57BL/6J-b2b2025Clo
b2b2025.2Clo/b2b2025.2CloC57BL/6J-b2b2025.2Clo
EFIC Summaryb2b2025Clo/b2b2025CloC57BL/6J-b2b2025Clo
b2b2025.2Clo/b2b2025.2CloC57BL/6J-b2b2025.2Clo
Serial EFIC image stack in coronal plane of 2025-007-2 (E16.5) shows DORV, AVSD, spongy ventricles, aberrant right subclavian artery forming incomplete vascular ring
Click thumbnail to play movie.		b2b2025Clo/b2b2025CloC57BL/6J-b2b2025Clo
b2b2025.2Clo/b2b2025.2CloC57BL/6J-b2b2025.2Clo
Color flow spectral Doppler imaging of mutant 2025-007-2 (E16.5) in the frontal view shows AO and PA originate from RVb2b2025Clo/b2b2025CloC57BL/6J-b2b2025Clo
b2b2025.2Clo/b2b2025.2CloC57BL/6J-b2b2025.2Clo
Color flow spectral Doppler imaging of mutant 2025-007-2 (E16.5) in the transverse view shows AVSDb2b2025Clo/b2b2025CloC57BL/6J-b2b2025Clo
b2b2025.2Clo/b2b2025.2CloC57BL/6J-b2b2025.2Clo
Mutant 2025-007-2 (E16.5) has syndactyly of the right forelimb and micropthalmia of the right eyeb2b2025Clo/b2b2025CloC57BL/6J-b2b2025Clo
b2b2025.2Clo/b2b2025.2CloC57BL/6J-b2b2025.2Clo
Mutant 2025-007-2 (E16.5) has micropthalmiab2b2025Clo/b2b2025CloC57BL/6J-b2b2025Clo
b2b2025.2Clo/b2b2025.2CloC57BL/6J-b2b2025.2Clo
Mutant 2025-007-2 exhibits a duplex left kidney with two ureters. There are a few glomerular cysts in both kidneys and some minor dilations of a few tubulesb2b2025Clo/b2b2025CloC57BL/6J-b2b2025Clo
b2b2025.2Clo/b2b2025.2CloC57BL/6J-b2b2025.2Clo
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/16/2024
MGI 6.23 		The Jackson Laboratory