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Phenotype Images associated with this Allele
Nomenclature
Symbol: Sox11tm1.1Gan
Name: SRY (sex determining region Y)-box 11; targeted mutation 1.1, Lin Gan
MGI ID: MGI:5518640
Synonyms: Sox11loxP
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Sox11tm1.1Gan/Sox11tm1.1Gan Tg(EIIa-cre)C5379Lmgd/0 mutants display cleft palate with retardation to palatal shelf elevationSox11tm1.1Gan/Sox11tm1.1Gan
Tg(EIIa-cre)C5379Lmgd/0		involves: 129S6/SvEvTac * C57BL/6 * FVB/N
Shorter mandible and displaced tongue position obstructs palatal elevation in Sox11tm1.1Gan/Sox11tm1.1Gan Tg(EIIa-cre)C5379Lmgd/0 mutantsSox11tm1.1Gan/Sox11tm1.1Gan
Tg(EIIa-cre)C5379Lmgd/0		involves: 129S6/SvEvTac * C57BL/6 * FVB/N
Cell proliferation in the mandibular mesenchyme is reduced in Sox11tm1.1Gan/Sox11tm1.1Gan Tg(EIIa-cre)C5379Lmgd/0 embryosSox11tm1.1Gan/Sox11tm1.1Gan
Tg(EIIa-cre)C5379Lmgd/0		involves: 129S6/SvEvTac * C57BL/6 * FVB/N
Cell proliferation of the palatal shelf is reduced in Sox11tm1.1Gan/Sox11tm1.1Gan Tg(EIIa-cre)C5379Lmgd/0 miceSox11tm1.1Gan/Sox11tm1.1Gan
Tg(EIIa-cre)C5379Lmgd/0		involves: 129S6/SvEvTac * C57BL/6 * FVB/N
Decrease in retinal ganglion cells in single Sox11tm1.1Gan and Sox4tm1Vlf homozygous conditional mutants and abolishment of retinal ganglion cells in Sox11tm1.1Gan/Sox11tm1.1Gan Sox4tm1Vlf/Sox4tm1Vlf Tg(Six3-cre)69Frty/0 retinasSox11tm1.1Gan/Sox11tm1.1Gan
Tg(Six3-cre)69Frty/0		involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * DBA/2
Sox11tm1.1Gan/Sox11tm1.1Gan
Sox4tm1Vlf/Sox4tm1Vlf
Tg(Six3-cre)69Frty/0		involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 * DBA/2
Sox4tm1Vlf/Sox4tm1Vlf
Tg(Six3-cre)69Frty/0		involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * C57BL/6J * DBA/2
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory