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Phenotype Images associated with this Allele
Nomenclature
Symbol: b2b1249Clo
Name: Mutant line 1249; Bench to Bassinet Program (B2B/CVDC), mutation 1249 Cecilia Lo
MGI ID: MGI:5311391
Synonyms: Cherry Garcia
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Persistent truncus arteriosus (PTA) and right aortic arch (RAA) in mutant 1249-007-1 (E16.5)b2b1249Clo/b2b1249CloC57BL/6J-b2b1249Clo
Persistent truncus arteriosus (PTA) and right aortic arch (RAA) in mutant 1249-007-1 (E16.5)b2b1249Clo/b2b1249CloC57BL/6J-b2b1249Clo
Central polydactyly in mutant 1249-007-1 (E16.5)b2b1249Clo/b2b1249CloC57BL/6J-b2b1249Clo
Central polydactyly in mutant 1249-007-1 (E16.5)b2b1249Clo/b2b1249CloC57BL/6J-b2b1249Clo
EFIC Summaryb2b1249Clo/b2b1249CloC57BL/6J-b2b1249Clo
Serial 2D EFIC image stack in the coronal plane of mutant 1249-007-1 (E16.5) reveals DORV, AVSD, hypoplastic pulmonary artery (PA), right aortic arch forming incomplete vascular ring with aberrant left subclavian artery, and hypoplastic lung
Click thumbnail to play movie.
b2b1249Clo/b2b1249CloC57BL/6J-b2b1249Clo
Serial 2D EFIC image stack in the coronal plane of mutant 1249-007-1 (E16.5) reveals DORV, AVSD, hypoplastic pulmonary artery (PA), right aortic arch, aberrant left subclavian artery forming incomplete vascular ring, and hypoplastic lung
Click thumbnail to play movie.
b2b1249Clo/b2b1249CloC57BL/6J-b2b1249Clo
Serial 2D EFIC image stack in the sagittal plane of mutant 1249-007-1 (E16.5) reveals DORV, AVSD, hypoplastic pulmonary artery (PA), right aortic arch forming incomplete vascular ring with aberrant left subclavian artery, and hypoplastic lung
Click thumbnail to play movie.
b2b1249Clo/b2b1249CloC57BL/6J-b2b1249Clo
Mutant 1249-002-NC displays levocardia, ambiguous lung lobation and malpositioning of the outflow tractb2b1249Clo/b2b1249CloC57BL/6J-b2b1249Clo
EFIC Summaryb2b1249Clo/b2b1249CloC57BL/6J-b2b1249Clo
Serial 2D EFIC image stack of 1249-002NC in the coronal plane reveals right aortic artch, perimembranous VSD
Click thumbnail to play movie.
b2b1249Clo/b2b1249CloC57BL/6J-b2b1249Clo
EFIC Summaryb2b1249Clo/b2b1249CloC57BL/6J-b2b1249Clo
Serial 2D EFIC image stack of 1249-002-NB in coronal plane reveals overriding aorta, perimembranous VSD with outlet extension, small aortic valve, hypoplastic ascending aorta, interrupted aortic arch (type B), PDA, aberrant right subclavian artery running behind esophagus forming incomplete vascular ring, Biventricular hypertrophy
Click thumbnail to play movie.
b2b1249Clo/b2b1249CloC57BL/6J-b2b1249Clo

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory