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Phenotype Images associated with this Transgene
Nomenclature
Symbol: Tg(PDGFB-LRRK2*G2019S)340Djmo
Name: transgene insertion 340, Darren Moore
MGI ID: MGI:4950671
Synonyms: G2019S-LRRK2
Images for
Allele
Click images for details
Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Progressive loss of substantia nigra dopaminergic neurons in Tg(PDGFB-LRRK2*G2019S)340Djmo/0 transgenic miceTg(PDGFB-LRRK2*G2019S)340Djmo/0involves: C3H/HeJ * C57BL/6J
Reduced neuritic complexity of dopaminergic neurons in Tg(PDGFB-LRRK2*G2019S)340Djmo/0 miceTg(PDGFB-LRRK2*G2019S)340Djmo/0involves: C3H/HeJ * C57BL/6J
Autophagic vacuoles in Tg(PDGFB-LRRK2*G2019S)340Djmo/0 cerebral cortexTg(PDGFB-LRRK2*G2019S)340Djmo/0involves: C3H/HeJ * C57BL/6J
Mitochondrial abnormalities in Tg(PDGFB-LRRK2*G2019S)340Djmo/0 miceTg(PDGFB-LRRK2*G2019S)340Djmo/0involves: C3H/HeJ * C57BL/6J
Accumulation of autophagic vacuoles in the striatum of Tg(PDGFB-LRRK2*G2019S)340Djmo/0 miceTg(PDGFB-LRRK2*G2019S)340Djmo/0involves: C3H/HeJ * C57BL/6J
Autophagic vacuoles accumulate in neuronal soma and axonal proceses in Tg(PDGFB-LRRK2*G2019S)340Djmo/0 miceTg(PDGFB-LRRK2*G2019S)340Djmo/0involves: C3H/HeJ * C57BL/6J

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/18/2022
MGI 6.17
The Jackson Laboratory