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Phenotype Images associated with this Allele
Nomenclature
Symbol: Sox2tm1.1Lan
Name: SRY (sex determining region Y)-box 2; targeted mutation 1.1, Richard A Lang
MGI ID: MGI:4366453
Synonyms: Sox2loxP, Sox2tm1.1Apdn
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Sox2tm1.1Lan/Sox2tm1.1Lan Tg(Scgb1a1-cre)1Kkw/0 mice show cuboidal-to-squamous epithelium lacking goblet, Clara and ciliated cells in the conducting airway epitheliumSox2tm1.1Lan/Sox2tm1.1Lan
Tg(Scgb1a1-cre)1Kkw/0
involves: 129/Sv * C57BL/6
Impaired goblet cell differentiation after pulmonary allergen sensitization in Sox2tm1.1Lan/Sox2tm1.1Lan Tg(Scgb1a1-cre)1Kkw/0 miceSox2tm1.1Lan/Sox2tm1.1Lan
Tg(Scgb1a1-cre)1Kkw/0
involves: 129/Sv * C57BL/6

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/12/2022
MGI 6.17
The Jackson Laboratory