Phenotype Images associated with this Allele - MGI

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Phenotype Images associated with this Allele

Nomenclature

Symbol:	Sox2^tm1.1Lan
Name:	SRY (sex determining region Y)-box 2; targeted mutation 1.1, Richard A Lang
MGI ID:	MGI:4366453
Synonyms:	Sox2^loxP, Sox2^tm1.1Apdn

Images for
Allele

Click images for details

Image	Caption	Genotypes involving this allele
Image	Caption	Allelic Composition	Genetic Background
	Sox2^tm1.1Lan/Sox2^tm1.1Lan Tg(Scgb1a1-cre)1Kkw/0 mice show cuboidal-to-squamous epithelium lacking goblet, Clara and ciliated cells in the conducting airway epithelium	Sox2^tm1.1Lan/Sox2^tm1.1Lan Tg(Scgb1a1-cre)1Kkw/0	involves: 129/Sv * C57BL/6
	Impaired goblet cell differentiation after pulmonary allergen sensitization in Sox2^tm1.1Lan/Sox2^tm1.1Lan Tg(Scgb1a1-cre)1Kkw/0 mice	Sox2^tm1.1Lan/Sox2^tm1.1Lan Tg(Scgb1a1-cre)1Kkw/0	involves: 129/Sv * C57BL/6

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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