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Phenotype Images associated with this Allele
Nomenclature
Symbol: Apctm1Rsmi
Name: APC, WNT signaling pathway regulator; targeted mutation 1, Ron Smits
MGI ID: MGI:3848479
Synonyms: Apc15lox, Apc16lox, Apcex15lox, Apctm1Ecrm
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Skeletogenesis is severely impaired in Apctm1Rsmi/Apctm1Rsmi Tg(Col2a1-cre)1Rsjo/0 miceApctm1Rsmi/Apctm1Rsmi
Tg(Col2a1-cre)1Rsjo/0		involves: 129P2/OlaHsd * FVB/N
Skeletal abnormalities in Apctm1Rsmi/Apctm1Rsmi Tg(Col2a1-cre)1Rsjo/0 miceApctm1Rsmi/Apctm1Rsmi
Tg(Col2a1-cre)1Rsjo/0		involves: 129P2/OlaHsd * FVB/N
Abnormal axial skeleton formation in E12.5 Apctm1Rsmi/Apctm1Rsmi Tg(Col2a1-cre)1Rsjo/0 embryosApctm1Rsmi/Apctm1Rsmi
Tg(Col2a1-cre)1Rsjo/0		involves: 129P2/OlaHsd * FVB/N
No chondrogenic and osteogenic differentiation in the developing Apctm1Rsmi/Apctm1Rsmi Tg(Col2a1-cre)1Rsjo/0 humerusApctm1Rsmi/Apctm1Rsmi
Tg(Col2a1-cre)1Rsjo/0		involves: 129P2/OlaHsd * FVB/N
Enhanced osteoblast formation and mineral deposition in developing Apctm1Rsmi/Apctm1Rsmi Tg(Col2a1-cre)1Rsjo/0 proximal ribsApctm1Rsmi/Apctm1Rsmi
Tg(Col2a1-cre)1Rsjo/0		involves: 129P2/OlaHsd * FVB/N
Dedifferentiation in the nasal septum of Apctm1Rsmi/Apctm1Rsmi Tg(Col2a1-cre)1Rsjo/0 fetuses at E16.5Apctm1Rsmi/Apctm1Rsmi
Tg(Col2a1-cre)1Rsjo/0		involves: 129P2/OlaHsd * FVB/N
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory