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Phenotype Images associated with this Allele
Nomenclature
Symbol: Gbatm2Karl
Name: glucosidase, beta, acid; targeted mutation 2, Stefan Karlsson
MGI ID: MGI:3764510
Synonyms: gbalnl
Images for
Allele
Click images for details
Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Gbatm2Karl/Gbatm2Karl Tg(KRT14-cre)8Brn/? mice display a severe and rapidly progressive neurological diseaseGbatm2Karl/Gbatm2Karl
Tg(KRT14-cre)8Brn/?
involves: 129S1/Sv * 129X1/SvJ * FVB/N
Gbatm2Karl/Gbatm2Karl (upper left) mice display a lethal skin phenotype whileGbatm2Karl/Gbatm2Karl Tg(KRT14-cre)8Brn/? (lower) mice display paralysisGbatm2Karl/Gbatm2Karlinvolves: 129S1/Sv * 129X1/SvJ
Gbatm2Karl/Gbatm2Karl
Tg(KRT14-cre)8Brn/?
involves: 129S1/Sv * 129X1/SvJ * FVB/N
Gbatm1Karl/Gbatm1Karl Tg(Nes-cre)1Kln/? mice exhibit a more profound activation and proliferation of microglial cells than Gbatm2Karl/Gbatm2Karl Tg(KRT14-cre)8Brn/? miceGbatm2Karl/Gbatm2Karl
Tg(KRT14-cre)8Brn/?
involves: 129S1/Sv * 129X1/SvJ * FVB/N
Gbatm1Karl/Gbatm1Karl
Tg(Nes-cre)1Kln/?
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
Gbatm2Karl/Gbatm2Karl Tg(KRT14-cre)8Brn/? mice display Gaucher cells in the liver and spleenGbatm2Karl/Gbatm2Karl
Tg(KRT14-cre)8Brn/?
involves: 129S1/Sv * 129X1/SvJ * FVB/N
Neuronal loss in Gbatm2Karl/Gbatm2Karl Tg(KRT14-cre)8Brn/? miceGbatm2Karl/Gbatm2Karl
Tg(KRT14-cre)8Brn/?
involves: 129S1/Sv * 129X1/SvJ * FVB/N
Gbatm2Karl/Gbatm2Karl Tg(KRT14-cre)8Brn/? mice display astrogliosis and abnormal microgliaGbatm2Karl/Gbatm2Karl
Tg(KRT14-cre)8Brn/?
involves: 129S1/Sv * 129X1/SvJ * FVB/N

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory