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Phenotype Images associated with this Transgene
Nomenclature
Symbol: Tg(Itgax-cre)1-1Reiz
Name: transgene insertion 1-1, Boris Reizis
MGI ID: MGI:3763248
Synonyms: Cd11c-cre, CD11cCre, CD11cCreT
Images for
Allele
Click images for details
Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Lupus-like autoimmune disease in Lyntm1Sor/Lyntm1Sor and Lyntm1.1Calo/Lyntm1.1Calo Top2aGt(PST14568)Mfgc/0 miceLyntm1Sor/Lyntm1Sorinvolves: 129S4/SvJaeSor
Lyntm1.1Calo/Lyntm1.1Calo
Tg(Itgax-cre)1-1Reiz/0
involves: 129P2/OlaHsd * C57BL/6 * CBA
By 8 months, severe leukocyte infiltration is seen in the lungs, liver and skin of Lyntm1Sor/Lyntm1Sor mice but not Lyntm1.1Calo/Lyntm1.1Calo Tg(Itgax-cre)1-1Reiz/0 miceLyntm1Sor/Lyntm1Sorinvolves: 129S4/SvJaeSor
Lyntm1.1Calo/Lyntm1.1Calo
Tg(Itgax-cre)1-1Reiz/0
involves: 129P2/OlaHsd * C57BL/6 * CBA
Splenomegaly and lymphadenopathy in Lyntm1Sor/Lyntm1Sor and Lyntm1.1Calo/Lyntm1.1Calo Tg(Itgax-cre)1-1Reiz/0 miceLyntm1Sor/Lyntm1Sorinvolves: 129S4/SvJaeSor
Lyntm1.1Calo/Lyntm1.1Calo
Tg(Itgax-cre)1-1Reiz/0
involves: 129P2/OlaHsd * C57BL/6 * CBA

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/16/2021
MGI 6.17
The Jackson Laboratory