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Phenotype Images associated with this Allele
Nomenclature
Symbol: Muc2wnn
Name: mucin 2; winnie
MGI ID: MGI:3614806
Images for
Allele
Click images for details
Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Fewer goblet cells in the intestines of Muc2wnn/Muc2wnn mice and reduction in secreted mucusMuc2wnn/Muc2wnnC57BL/6-Muc2wnn
Schematic showing locations of the Muc2wnn and Muc2eey mutations
Spontaneous colitis in Muc2wnn/Muc2wnn miceMuc2wnn/Muc2wnnC57BL/6-Muc2wnn
Increased intestinal proliferation in Muc2wnn/Muc2wnn miceMuc2wnn/Muc2wnnC57BL/6-Muc2wnn
Increased apoptosis in the small and large intestine of Muc2wnn/Muc2wnn miceMuc2wnn/Muc2wnnC57BL/6-Muc2wnn
Endoplasmic reticulum stress in the intestinal epithelium of Muc2wnn/Muc2wnn and Muc2eey/Muc2eey miceMuc2wnn/Muc2wnnC57BL/6-Muc2wnn
Muc2eey/Muc2eeyC57BL/6-Muc2eey
Abnormal vacuolization of goblet cells in Muc2wnn/Muc2+ intestineMuc2wnn/Muc2+C57BL/6-Muc2wnn

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory