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Phenotype Images associated with this Allele
Nomenclature
Symbol: Stat3tm1Flv
Name: signal transducer and activator of transcription 3; targeted mutation 1, Richard A Flavell
MGI ID: MGI:2451328
Synonyms: STAT3f, STAT3KO
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Neural-specific STAT3 deletion results in severe obesity in Stat3tm1Flv/Stat3tm1Flv Tg(Nes-cre)1Kln/0 mice similar to that seen in Leprdb/Leprdb miceLeprdb/Leprdbinvolves: C57BLKS/J
Stat3tm1Flv/Stat3tm1Flv
Tg(Nes-cre)1Kln/0		involves: C57BL/6 * SJL
Hyperphagia and fatty livers in Stat3tm1Flv/Stat3tm1Flv Tg(Nes-cre)1Kln/0 miceStat3tm1Flv/Stat3tm1Flv
Tg(Nes-cre)1Kln/0		involves: C57BL/6 * SJL
Stat3tm1Flv/Stat3tm1Flv Tg(Nes-cre)1Kln/0 mice are infertile, hypogonadal and shortStat3tm1Flv/Stat3tm1Flv
Tg(Nes-cre)1Kln/0		involves: C57BL/6 * SJL
Adipose tissue is altered in Stat3tm1Flv/Stat3tm1Flv Tg(Nes-cre)1Kln/0 miceStat3tm1Flv/Stat3tm1Flv
Tg(Nes-cre)1Kln/0		involves: C57BL/6 * SJL
Crohn's disease-like pathogenesis in Stat3tm1Flv/Stat3tm1Flv Tg(Tek-cre)12Flv/0 miceStat3tm1Flv/Stat3tm1Flv
Tg(Tek-cre)12Flv/0		involves: 129 * C3H * C57BL/6
Liver inflammation in Stat3tm1Flv/Stat3tm1Flv Tg(Tek-cre)12Flv/0 miceStat3tm1Flv/Stat3tm1Flv
Tg(Tek-cre)12Flv/0		involves: 129 * C3H * C57BL/6
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory