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Phenotype Images associated with this Transgene
Nomenclature
Symbol: Tg(Prrx1-cre)1Cjt
Name: transgene insertion 1, Clifford J Tabin
MGI ID: MGI:2450929
Synonyms: Prx1cre, Prx1-cre, Prx1Cre, Prx-1 Cre, Prx-cre, Tg[Prx1-cre]1Cjt
Images for
Allele
Click images for details
Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Impairment of ossification in various conditional Sp7tm1Rnis/Sp7tm1Rnis miceSp7tm1Rnis/Sp7tm1Rnis
Tg(Col11a2-cre)1Ntsu/0		involves: C57BL * C57BL/6 * CBA/JNCrlj * DBA/2
Sp7tm1Rnis/Sp7tm1Rnis
Tg(Col2a1-cre)1Bhr/0		involves: C57BL * C57BL/6 * CBA/JNCrlj * SJL
Sp7tm1Rnis/Sp7tm1Rnis
Tg(Prrx1-cre)1Cjt/0		involves: C57BL * C57BL/6 * CBA/JNCrlj * SJL/J
Rspo2ftls/Rspo2ftls Rspo3tm1.1Jcob/Rspo3tm1.2Jcob Tg(Prrx1-cre)1Cjt/0 double mutants have more severe limb defects than single mutantsRspo3tm1.1Jcob/Rspo3tm1.2Jcob
Tg(Prrx1-cre)1Cjt/0		involves: 129S6/SvEvTac * C57BL/6 * CD-1 * SJL
Rspo2ftls/Rspo2ftls
Rspo3tm1.1Jcob/Rspo3tm1.2Jcob
Tg(Prrx1-cre)1Cjt/0		involves: 129S6/SvEvTac * C57BL/6 * CD-1 * SJL
Rspo2ftls/Rspo2ftlsNot Specified
Limb abnormalities in Rspo2ftls/Rspo2ftls and Rspo2ftls/Rspo2ftls Rspo3tm1.1Jcob/Rspo3tm1.2Jcob Tg(Prrx1-cre)1Cjt/0 newbornsRspo2ftls/Rspo2ftls
Rspo3tm1.1Jcob/Rspo3tm1.2Jcob
Tg(Prrx1-cre)1Cjt/0		involves: 129S6/SvEvTac * C57BL/6 * CD-1 * SJL
Rspo2ftls/Rspo2ftlsNot Specified
Skeletal abnormalities in Porcntm1.1Vdv/Y Tg(Prrx1-cre)1Cjt/0 micePorcntm1.1Vdv/Y
Tg(Prrx1-cre)1Cjt/0		involves: 129S4/SvJaeSor * 129S5/SvEvBrd * C57BL/6 * SJL/J
Tissue-specific Porcntm1.1Lcm deletion phenotypes include skeletal defects and skin abnormalitiesPorcntm1.1Lcm/Y
Tg(Prrx1-cre)1Cjt/0		involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL/J
Porcntm1.1Lcm/Y
Tg(Msx2-cre)5Rem/0		involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Limb deformities in Vcantm1.1Hwat/Vcantm1.1Hwat Tg(Prrx1-cre)1Cjt/0 miceVcantm1.1Hwat/Vcantm1.1Hwat
Tg(Prrx1-cre)1Cjt/0		involves: C57BL/6 * C57BL/6J * SJL/J
Vcantm1.1Hwat/Vcantm1.1Hwat Tg(Prrx1-cre)1Cjt/0 digits exhibit tilted joint and delayed cartilage developmentVcantm1.1Hwat/Vcantm1.1Hwat
Tg(Prrx1-cre)1Cjt/0		involves: C57BL/6 * C57BL/6J * SJL/J
Versican is absent in Vcantm1.1Hwat/Vcantm1.1Hwat Tg(Prrx1-cre)1Cjt/0 digitsVcantm1.1Hwat/Vcantm1.1Hwat
Tg(Prrx1-cre)1Cjt/0		involves: C57BL/6 * C57BL/6J * SJL/J
Micromass culture from Vcantm1.1Hwat/Vcantm1.1Hwat Tg(Prrx1-cre)1Cjt/0 mice exhibits delayed chondrocyte differentiationVcantm1.1Hwat/Vcantm1.1Hwat
Tg(Prrx1-cre)1Cjt/0		involves: C57BL/6 * C57BL/6J * SJL/J
Digit abnormalities in Vcantm1.1Hwat/Vcantm1.1Hwat Tg(Prrx1-cre)1Cjt/0 miceVcantm1.1Hwat/Vcantm1.1Hwat
Tg(Prrx1-cre)1Cjt/0		involves: C57BL/6 * C57BL/6J * SJL/J
Mice deficient singly or in various combinations of Bmp2, Bmp4 and Bmp7 display limb defectsBmp2tm1Cjt/Bmp2+
Bmp4tm1Jfm/Bmp4tm1Jfm
Tg(Prrx1-cre)1Cjt/0		involves: 129S4/SvJaeSor * C57BL/6 * SJL
Bmp2tm1Cjt/Bmp2tm1Cjt
Bmp4tm1Jfm/Bmp4+
Tg(Prrx1-cre)1Cjt/0		involves: 129S4/SvJaeSor * C57BL/6 * SJL
Bmp2tm1Cjt/Bmp2tm1Cjt
Bmp4tm1Jfm/Bmp4tm1Jfm
Tg(Prrx1-cre)1Cjt/0		involves: 129S4/SvJaeSor * C57BL/6 * SJL
Bmp2tm1Cjt/Bmp2tm1Cjt
Tg(Prrx1-cre)1Cjt/0		involves: C57BL/6 * SJL
Bmp4tm1Jfm/Bmp4tm1Jfm
Tg(Prrx1-cre)1Cjt/0		involves: 129S4/SvJaeSor * C57BL/6 * SJL
Bmp2tm1Cjt/Bmp2tm1Cjt
Bmp7tm1Rob/Bmp7tm1Rob
Tg(Prrx1-cre)1Cjt/0		involves: 129S/SvEv * C57BL/6 * SJL
Mice lacking Bmp2 in the limbs exhibit syndactylyBmp2tm1Cjt/Bmp2tm1Cjt
Tg(Prrx1-cre)1Cjt/0		involves: C57BL/6 * SJL
Osteogenesis begins during early embryonic development in mice lacking Bmp2 and Bmp4 in the limbsBmp2tm1Cjt/Bmp2tm1Cjt
Bmp4tm1Jfm/Bmp4tm1Jfm
Tg(Prrx1-cre)1Cjt/0		involves: 129S4/SvJaeSor * C57BL/6 * SJL
Defects in bone formation in mice lacking Bmp2 and Bmp4 in the limbsBmp2tm1Cjt/Bmp2tm1Cjt
Bmp4tm1Jfm/Bmp4tm1Jfm
Tg(Prrx1-cre)1Cjt/0		involves: 129S4/SvJaeSor * C57BL/6 * SJL
Limb syndactyly in mice lacking Bmp2 and Bmp4Bmp2tm1Cjt/Bmp2tm1Cjt
Bmp4tm1Jfm/Bmp4tm1Jfm
Tg(Prrx1-cre)1Cjt/0		involves: 129S4/SvJaeSor * C57BL/6 * SJL
Limb phenotype of Shox2tm1Ddu/Shox2tm1.1Ddu Tg(Prrx1-cre)1Cjt miceShox2tm1Ddu/Shox2tm1.1Ddu
Tg(Prrx1-cre)1Cjt/0		involves: 129S2/SvPas * C57BL/6J * SJL/J
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/16/2024
MGI 6.23 		The Jackson Laboratory