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Phenotype Images associated with this Transgene
Nomenclature
Symbol: Tg(Myh6-cre)2182Mds
Name: transgene insertion 2182, Michael D Schneider
MGI ID: MGI:2386742
Synonyms: alphaMhc-Cre, alpha-MHC-Cre+, alphaMyHC-Cre, MCH-cre, MHCalphaCre, MHCcre, MHC-Cre, Tg(Myhca-cre)2182Mds
Images for
Allele
Click images for details
Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Lethal cardiomyopathy in Yap1tm1.1Eno/Yap1tm1.1Eno Tg(Myh6-cre)2182Mds/0 miceYap1tm1.1Eno/Yap1tm1.1Eno
Tg(Myh6-cre)2182Mds/0
involves: 129S/SvEv * FVB/N
Cardiomyopathy in Wwtr1tm1.2Eno/Wwtr1tm1.2Eno Yap1tm1.1Eno/Yap1+ Tg(Myh6-cre)2182Mds/0 miceWwtr1tm1.1Eno/Wwtr1tm1.1Eno
Yap1tm1.1Eno/Yap1+
Tg(Myh6-cre)2182Mds/0
involves: 129S/SvEv * FVB/N
Cardiomyopathy in Wwtr1tm1.2Eno/Wwtr1+ Yap1tm1.1Eno/Yap1tm1.1Eno Tg(Myh6-cre)2182Mds/0 miceWwtr1tm1.1Eno/Wwtr1+
Yap1tm1.1Eno/Yap1tm1.1Eno
Tg(Myh6-cre)2182Mds/0
involves: 129S/SvEv * FVB/N
Impaired neonatal heart regeneration in Yap1tm1.1Eno/Yap1tm1.1Eno Tg(Myh6-cre)2182Mds/0 miceYap1tm1.1Eno/Yap1tm1.1Eno
Tg(Myh6-cre)2182Mds/0
involves: 129S/SvEv * FVB/N
Wwtr1tm1.1Eno/Wwtr1tm1.1Eno Yap1tm1.1Eno/Yap1tm1.1Eno Tg(Myh6-cre)2182Mds/0 mice exhibit cardiac abnormalities and Wwtr1tm1.1Eno/Wwtr1+ Yap1tm1.1Eno/Yap1tm1.1Eno Tg(Myh6-cre)2182Mds/0 hearts show defects in proliferation and survivalWwtr1tm1.1Eno/Wwtr1+
Yap1tm1.1Eno/Yap1tm1.1Eno
Tg(Myh6-cre)2182Mds/0
involves: 129S/SvEv * FVB/N
Wwtr1tm1.1Eno/Wwtr1tm1.1Eno
Yap1tm1.1Eno/Yap1tm1.1Eno
Tg(Myh6-cre)2182Mds/0
involves: 129S/SvEv * FVB/N
Sarcomere maturation is attenuated in Rhebtm1.1Otsu/Rhebtm1.1Otsu Tg(Myh6-cre)2182Mds/0 heartsRhebtm1.1Otsu/Rhebtm1.1Otsu
Tg(Myh6-cre)2182Mds/0
involves: 129 * C57BL/6J * FVB/N
Hearts of Gata4tm1.1Wtp/Gata4tm1Grg Tg(Myh6-cre)2182Mds/0 mice appear normalGata4tm1Grg/Gata4tm1.1Wtp
Tg(Myh6-cre)2182Mds/0
involves: 129 * C57BL/6 * FVB/N
Increased cardiac fibrosis in Capns1tm1.1Otsu/Capns1tm1.1Otsu Tg(Myh6-cre)2182Mds/0 mice after transverse aortic constrictionCapns1tm1.1Otsu/Capns1tm1.1Otsu
Tg(Myh6-cre)2182Mds/0
involves: C57BL/6J * FVB/N
Plasma membrane damage in Capns1tm1.1Otsu/Capns1tm1.1Otsu Tg(Myh6-cre)2182Mds/0 heartsCapns1tm1.1Otsu/Capns1tm1.1Otsu
Tg(Myh6-cre)2182Mds/0
involves: C57BL/6J * FVB/N
Cardiomyocyte-specific deletion of Klf5 does not alter pressure overload-induced hypertrophy in Klf5tm2.1Rng/Klf5tm2.1Rng Tg(Myh6-cre)2182Mds/0 miceKlf5tm2.1Rng/Klf5tm2.1Rng
Tg(Myh6-cre)2182Mds/0
involves: C57BL/6 * FVB/N
Increase in interstitial and perivascular collagen in Lpltm1Ijg/Lpltm1Ijg Tg(Myh6-cre)2182Mds/0 heartsLpltm1Ijg/Lpltm1Ijg
Tg(Myh6-cre)2182Mds/0
involves: FVB/N

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last database update
06/16/2015
MGI 5.22
The Jackson Laboratory