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Phenotype Images associated with this Transgene
Nomenclature
Symbol: Tg(Wnt1-cre)11Rth
Name: transgene insertion 11, David H Rowitch
MGI ID: MGI:2386570
Synonyms: Wnt1cre, Wnt1Cre, Wnt1-Cre, Wnt1::Cre
Images for
Allele
Click images for details
Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Reduced numbers of sympathetic and dorsal root ganglia neurons in Ikbkaptm1c(KOMP)Wtsi/Ikbkaptm1c(KOMP)Wtsi Tg(Wnt1-cre)11Rth/0 fetusesIkbkaptm1c(KOMP)Wtsi/Ikbkaptm1c(KOMP)Wtsi
Tg(Wnt1-cre)11Rth/0
involves: C57BL/6J * C57BL/6N * CBA/J
Ikbkaptm1c(KOMP)Wtsi/Ikbkaptm1c(KOMP)Wtsi Tg(Wnt1-cre)11Rth/0 fetuses exhibit a decreased inferior facial angle and increased mandibular retropositionIkbkaptm1c(KOMP)Wtsi/Ikbkaptm1c(KOMP)Wtsi
Tg(Wnt1-cre)11Rth/0
involves: C57BL/6J * C57BL/6N * CBA/J
Reduction in the number of TH+ neurons in the dorsal root ganglia of Ikbkaptm1c(KOMP)Wtsi/Ikbkaptm1c(KOMP)Wtsi Tg(Wnt1-cre)11Rth/0 embryosIkbkaptm1c(KOMP)Wtsi/Ikbkaptm1c(KOMP)Wtsi
Tg(Wnt1-cre)11Rth/0
involves: C57BL/6J * C57BL/6N * CBA/J
Reduction in the number of TrkA+ fibers in the dorsal horn of the spinal cord and in the skin of Ikbkaptm1c(KOMP)Wtsi/Ikbkaptm1c(KOMP)WtsiTg(Wnt1-cre)11Rth/0 fetusesIkbkaptm1c(KOMP)Wtsi/Ikbkaptm1c(KOMP)Wtsi
Tg(Wnt1-cre)11Rth/0
involves: C57BL/6J * C57BL/6N * CBA/J
Reduced sympathetic and parasympathetic innervation of the submandibular gland in Ikbkaptm1c(KOMP)Wtsi/Ikbkaptm1c(KOMP)Wtsi Tg(Wnt1-cre)11Rth/0 embryosIkbkaptm1c(KOMP)Wtsi/Ikbkaptm1c(KOMP)Wtsi
Tg(Wnt1-cre)11Rth/0
involves: C57BL/6J * C57BL/6N * CBA/J
Mandibular hypoplasia and cleft palate in Map3k7tm1Mis/Map3k7tm1MisTg(Wnt1-cre)11Rth/0 miceMap3k7tm1Mis/Map3k7tm1Mis
Tg(Wnt1-cre)11Rth/0
involves: C57BL/6J * CBA/J
Palatal shelves of Map3k7tm1Mis/Map3k7tm1Mis Tg(Wnt1-cre)11Rth/0 mice show delayed rugal formationMap3k7tm1Mis/Map3k7tm1Mis
Tg(Wnt1-cre)11Rth/0
involves: C57BL/6J * CBA/J
Ror1tm1.1Meg/Ror1tm1.1Meg Ror2tm1.1Meg/Ror2tm1.1Meg Tg(Wnt1-cre)11Rth/0 embryos exhibit sympathetic axon branching defectsRor1tm1.1Meg/Ror1tm1.1Meg
Ror2tm1.1Meg/Ror2tm1.1Meg
Tg(Wnt1-cre)11Rth/0
involves: 129S4/SvJae * C57BL/6J * CBA/J
Craniofacial malformation in Ext1tm1Yama/Ext1tm1YamaTg(Wnt1-cre)11Rth/0 miceExt1tm1Yama/Ext1tm1Yama
Tg(Wnt1-cre)11Rth/0
B6.Cg-Ext1tm1Yama Tg(Wnt1-cre)11Rth
Peters-like anomaly in Ext1tm1Yama/Ext1tm1Yama Tg(Wnt1-cre)11Rth/0 miceExt1tm1Yama/Ext1tm1Yama
Tg(Wnt1-cre)11Rth/0
B6.Cg-Ext1tm1Yama Tg(Wnt1-cre)11Rth
Neural crest cell proliferation in the anterior chamber of Ext1tm1Yama/Ext1tm1Yama Tg(Wnt1-cre)11Rth/0 mice is disturbedExt1tm1Yama/Ext1tm1Yama
Tg(Wnt1-cre)11Rth/0
B6.Cg-Ext1tm1Yama Tg(Wnt1-cre)11Rth
Thin cornea and iridocorneal dysgenesis in Ext1tm1Yama/Ext1+ Tg(Wnt1-cre)11Rth/0 Tgfb2tm1Doe/Tgfb2+ miceExt1tm1Yama/Ext1+
Tg(Wnt1-cre)11Rth/0
Tgfb2tm1Doe/Tgfb2+
B6.Cg-Tgfb2tm1Doe Ext1tm1Yama Tg(Wnt1-cre)11Rth
Aberrant iridocorneal development in Ext1tm1Yama/Ext1+ Tg(Wnt1-cre)11Rth/0 Tgfb2tm1Doe/Tgfb2+ miceExt1tm1Yama/Ext1+
Tg(Wnt1-cre)11Rth/0
Tgfb2tm1Doe/Tgfb2+
B6.Cg-Tgfb2tm1Doe Ext1tm1Yama Tg(Wnt1-cre)11Rth
Skeletal image of newborn Sox9tm2Crm/Sox9tm2Crm Tg(Wnt1-cre)11Rth/0 miceSox9tm2Crm/Sox9tm2Crm
Tg(Wnt1-cre)11Rth/0
involves: 129S/SvEv * C57BL/6 * CBA
Skeletal preparations of wild-type and Sox9tm2Crm/Sox9tm2Crm Tg(Wnt1-cre)11Rth/0 embryosSox9tm2Crm/Sox9tm2Crm
Tg(Wnt1-cre)11Rth/0
involves: 129S/SvEv * C57BL/6 * CBA

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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory