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Phenotype Images associated with this Allele
Symbol: Cav3tm1Mls
Name: caveolin 3; targeted mutation 1, Michael P Lisanti
MGI ID: MGI:2180558
Synonyms: cav-3-, CAV3 -
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Cav3tm1Mls/Cav3tm1Mls hearts display progressive left ventricular wall thickeningCav3tm1Mls/Cav3tm1Mlsinvolves: 129/Sv * C57BL/6J * SJL
Cav3tm1Mls/Cav3tm1Mls heart tissue displays cardiac myocyte hypertrophy, interstitial/peri-vascular fibrosis and cellular infiltratesCav3tm1Mls/Cav3tm1Mlsinvolves: 129/Sv * C57BL/6J * SJL
Cav3tm1Mls/Cav3tm1Mls skeletal muscle lacks sarcolemmal caveolaeCav3tm1Mls/Cav3tm1Mlsinvolves: 129/Sv * C57BL/6J * SJL
Cav3tm1Mls/Cav3tm1Mls skeletal muscle displays variable fiber size and some necrotic fibersCav3tm1Mls/Cav3tm1Mlsinvolves: 129/Sv * C57BL/6J * SJL
Abnormal T-tubule system in Cav3tm1Mls/Cav3tm1Mls skeletal muscleCav3tm1Mls/Cav3tm1Mlsinvolves: 129/Sv * C57BL/6J * SJL

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.08
The Jackson Laboratory