Phenotype Images associated with this Allele - MGI

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Phenotype Images associated with this Allele

Nomenclature

Symbol:	Des^tm1Cap
Name:	desmin; targeted mutation 1, Yassemi Capetanaki
MGI ID:	MGI:2178321
Synonyms:	des^m1

Images for
Allele

Click images for details

Image	Caption	Genotypes involving this allele
Image	Caption	Allelic Composition	Genetic Background
	Cardiac fibrosis and calcification seen in Des^tm1Cap/Des^tm1Cap mice is reduced in Des^tm1Cap/Des^tm1Cap Tg(Bcl2)ACap/Tg(Bcl2)ACap and Des^tm1Cap/Des^tm1Cap Tg(Bcl2)BCap/Tg(Bcl2)BCap mice	Des^tm1Cap/Des^tm1Cap Tg(Bcl2)ACap/Tg(Bcl2)ACap	involves: 129S7/SvEvBrd * C57BL/6
		Des^tm1Cap/Des^tm1Cap Tg(Bcl2)BCap/Tg(Bcl2)BCap	involves: 129S7/SvEvBrd * C57BL/6
		Des^tm1Cap/Des^tm1Cap	involves: 129S7/SvEvBrd
	Ultrastructural cardiomyocyte abnormalities seen in Des^tm1Cap/Des^tm1Cap mice are reduced in Des^tm1Cap/Des^tm1Cap Tg(Bcl2)ACap/Tg(Bcl2)ACap mice	Des^tm1Cap/Des^tm1Cap Tg(Bcl2)BCap/Tg(Bcl2)BCap	involves: 129S7/SvEvBrd * C57BL/6
		Des^tm1Cap/Des^tm1Cap	involves: 129S7/SvEvBrd
	Myocardium degeneration and calcification in Des^tm1Cap/Des^tm1Cap mice	Des^tm1Cap/Des^tm1Cap	involves: 129S7/SvEvBrd * C57BL/6
	Progressive degeneration of cardiac muscle in Des^tm1Cap/Des^tm1Cap mice	Des^tm1Cap/Des^tm1Cap	involves: 129S7/SvEvBrd * C57BL/6
	Des^tm1Cap/Des^tm1Cap mice exhibit disorganized cardiac myofibrils	Des^tm1Cap/Des^tm1Cap	involves: 129S7/SvEvBrd * C57BL/6
	Skeletal muscle abnormalities in Des^tm1Cap/Des^tm1Cap mice	Des^tm1Cap/Des^tm1Cap	involves: 129S7/SvEvBrd * C57BL/6
	Severely disrupted skeletal myofibrils in Des^tm1Cap/Des^tm1Cap diaphragm	Des^tm1Cap/Des^tm1Cap	involves: 129S7/SvEvBrd * C57BL/6
	Smooth muscle abnormalities in Des^tm1Cap/Des^tm1Cap mice	Des^tm1Cap/Des^tm1Cap	involves: 129S7/SvEvBrd * C57BL/6

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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