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Phenotype Images associated with this Transgene
Nomenclature
Symbol: Tg(Ins2-cre)25Mgn
Name: transgene insertion 25, Mark A Magnuson
MGI ID: MGI:2176227
Synonyms: Ins2cre, Ins-Cre, M line, RIP2-cre, RIP2Cre, Rip-cre, RIPCre, [RIP]-Cre, RIP Cre, RIP-Cre, TgN(ins2-Cre)25Mgn
Images for
Allele
Click images for details
Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Low zinc content, insulin crystallization failure, and presence of atypical insulin granules in beta cells of Slc30a8tm1.1Htwt/Slc30a8tm1.1Htwt Tg(Ins2-cre)25Mgn/0 mice
Endoplasmic reticulum distention in Cdkal1tm1.2Tomik/Cdkal1tm1.2Tomik Tg(Ins2-cre)25Mgn/0 beta cellsCdkal1tm1.1Tomik/Cdkal1tm1.1Tomik
Tg(Ins2-cre)25Mgn/0
B6.Cg-Cdkal1tm1.1Tomik Tg(Ins2-cre)25Mgn
High fat diet-induced obesity causes impaired glucose tolerance and insulin secretion in Ghrtm1.1Dlr/Ghrtm1.1Dlr Tg(Ins2-cre)25Mgn/0 miceGhrtm1.1Dlr/Ghrtm1.1Dlr
Tg(Ins2-cre)25Mgn/0
involves: 129S4/SvJae * C3H * C57BL/6 * DBA
Reduced beta cell proliferation in obese Ghrtm1.1Dlr/Ghrtm1.1Dlr Tg(Ins2-cre)25Mgn/0 miceGhrtm1.1Dlr/Ghrtm1.1Dlr
Tg(Ins2-cre)25Mgn/0
involves: 129S4/SvJae * C3H * C57BL/6 * DBA

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory