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Phenotype Images associated with this Allele
Nomenclature
Symbol: Bmpr1btm1Kml
Name: bone morphogenetic protein receptor, type 1B; targeted mutation 1, Karen M Lyons
MGI ID: MGI:2158497
Synonyms: Bmpr1b-, Bmpr1bn, BmprIB -
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Skeletal abnormalities in Bmpr1btm1Kml/Bmpr1btm1Kml, Bmpr1atm2.1Bhr/Bmpr1atm2.1Bhr Tg(Col2a1-cre)1Bhr/?, and Bmpr1atm2.1Bhr/Bmpr1atm2.1Bhr Bmpr1btm1Kml/Bmpr1btm1Kml Tg(Col2a1-cre)1Bhr/? miceBmpr1btm1Kml/Bmpr1btm1Kmlinvolves: 129S/SvEv
Bmpr1atm2.1Bhr/Bmpr1atm2.1Bhr
Bmpr1btm1Kml/Bmpr1btm1Kml
Tg(Col2a1-cre)1Bhr/?		involves: 129S/SvEv * 129S7/SvEvBrd * C57BL/6 * SJL
Bmpr1atm2.1Bhr/Bmpr1atm2.1Bhr
Tg(Col2a1-cre)1Bhr/?		involves: 129S7/SvEvBrd * C57BL/6 * SJL
Impaired chondrocyte differentiation in Bmpr1atm2.1Bhr/Bmpr1atm2.1Bhr Bmpr1btm1Kml/Bmpr1btm1Kml Tg(Col2a1-cre)1Bhr/? miceBmpr1atm2.1Bhr/Bmpr1atm2.1Bhr
Bmpr1btm1Kml/Bmpr1btm1Kml
Tg(Col2a1-cre)1Bhr/?		involves: 129S/SvEv * 129S7/SvEvBrd * C57BL/6 * SJL
Impaired chondrogenesis and extracellular matrix expression in Bmpr1atm2.1Bhr/Bmpr1atm2.1Bhr Bmpr1btm1Kml/Bmpr1btm1Kml Tg(Col2a1-cre)1Bhr/? miceBmpr1atm2.1Bhr/Bmpr1atm2.1Bhr
Bmpr1btm1Kml/Bmpr1btm1Kml
Tg(Col2a1-cre)1Bhr/?		involves: 129S/SvEv * 129S7/SvEvBrd * C57BL/6 * SJL
Reduced rates of proliferation and cell survival in cartilage elements of Bmpr1atm2.1Bhr/Bmpr1atm2.1Bhr Bmpr1btm1Kml/Bmpr1btm1Kml Tg(Col2a1-cre)1Bhr/? embryosBmpr1atm2.1Bhr/Bmpr1atm2.1Bhr
Bmpr1btm1Kml/Bmpr1btm1Kml
Tg(Col2a1-cre)1Bhr/?		involves: 129S/SvEv * 129S7/SvEvBrd * C57BL/6 * SJL
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory