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Phenotype Images associated with this Allele
Nomenclature
Symbol: Mbtps1tm1Jdh
Name: membrane-bound transcription factor peptidase, site 1; targeted mutation 1, Jay D Horton
MGI ID: MGI:2156484
Synonyms: S1Pf
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Severe chondrodysplasia in Mbtps1tm1Jdh/Mbtps1tm1Jdh Tg(Col2a1-cre)1Bhr/0 miceMbtps1tm1Jdh/Mbtps1tm1Jdh
Tg(Col2a1-cre)1Bhr/0		involves: 129S6/SvEvTac * C57BL/6 * SJL
Lack of organized hypertrophy and endochondral bone formation in Mbtps1tm1Jdh/Mbtps1tm1Jdh Tg(Col2a1-cre)1Bhr/0 miceMbtps1tm1Jdh/Mbtps1tm1Jdh
Tg(Col2a1-cre)1Bhr/0		involves: 129S6/SvEvTac * C57BL/6 * SJL
Increased chondrocyte apoptosis and absence of vascular invasion in the skeletal elements of Mbtps1tm1Jdh/Mbtps1tm1Jdh Tg(Col2a1-cre)1Bhr/0 miceMbtps1tm1Jdh/Mbtps1tm1Jdh
Tg(Col2a1-cre)1Bhr/0		involves: 129S6/SvEvTac * C57BL/6 * SJL
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory