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Phenotype Images associated with this Allele
Nomenclature
Symbol: Eya1tm1Rilm
Name: EYA transcriptional coactivator and phosphatase 1; targeted mutation 1, Richard Maas
MGI ID: MGI:2150426
Synonyms: Eya1-
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Spectrum of abnormalities of great artery patterning in mice with null mutation of one or both copies of Six1tm1Mair and Eya1tm1RilmEya1tm1Rilm/Eya1tm1Rilminvolves: 129S1/Sv * 129X1/SvJ * C57BL/6
Eya1tm1Rilm/Eya1tm1Rilm
Six1tm1Mair/Six1tm1Mair
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Eya1tm1Rilm/Eya1tm1Rilm
Six1tm1Mair/Six1+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Eya1tm1Rilm/Eya1+
Six1tm1Mair/Six1tm1Mair
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Six1tm1Mair/Six1tm1Mairinvolves: 129S1/Sv * 129X1/SvJ * C57BL/6
Increased cell death in pharyngeal endoderm Six1tm1Mair/Six1tm1Mair Eya1tm1Rilm/Eya1tm1Rilm miceEya1tm1Rilm/Eya1tm1Rilm
Six1tm1Mair/Six1tm1Mair
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Hypoplastic outflow tract cushions in Six1tm1Mair/Six1tm1Mair Eya1tm1Rilm/Eya1tm1Rilm miceEya1tm1Rilm/Eya1tm1Rilm
Six1tm1Mair/Six1tm1Mair
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Cardiovascular defects in mice with mutations of one or both copies of Eya1tm1Rilm and Tbx1tm1BemEya1tm1Rilm/Eya1+
Tbx1tm1Bem/Tbx1+
involves: 129 * C57BL/6 * CD-1 * SJL
Eya1tm1Rilm/Eya1tm1Rilm
Tbx1tm1Bem/Tbx1+
involves: 129 * C57BL/6 * CD-1 * SJL
Craniofacial morphogenesis defects in mice with mutations of one or both copies of Six1tm1Mair and Eya1tm1RilmEya1tm1Rilm/Eya1tm1Rilm
Six1tm1Mair/Six1tm1Mair
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Eya1tm1Rilm/Eya1tm1Rilm
Six1tm1Mair/Six1+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Eya1tm1Rilm/Eya1+
Six1tm1Mair/Six1tm1Mair
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Six1tm1Mair/Six1tm1Mairinvolves: 129S1/Sv * 129X1/SvJ * C57BL/6

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
12/03/2019
MGI 6.14
The Jackson Laboratory