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Phenotype Images associated with this Transgene
Nomenclature
Symbol: Tg(EIIa-cre)C5379Lmgd
Name: transgene insertion C5379, Laboratory of Mammalian Genes and Development, Heiner Westphal
MGI ID: MGI:2137691
Synonyms: E2a-Cre, EIIa-cre, EIIaCre, EIIaCre deleter, EIIa Cretg, EII-cre, Ela-Cre, Ella:Cre, TgN(EIIa-Cre)C5379Lmgd
Images for
Allele
Click images for details
Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Sox11tm1.1Gan/Sox11tm1.1Gan Tg(EIIa-cre)C5379Lmgd/0 mutants display cleft palate with retardation to palatal shelf elevationSox11tm1.1Gan/Sox11tm1.1Gan
Tg(EIIa-cre)C5379Lmgd/0		involves: 129S6/SvEvTac * C57BL/6 * FVB/N
Shorter mandible and displaced tongue position obstructs palatal elevation in Sox11tm1.1Gan/Sox11tm1.1Gan Tg(EIIa-cre)C5379Lmgd/0 mutantsSox11tm1.1Gan/Sox11tm1.1Gan
Tg(EIIa-cre)C5379Lmgd/0		involves: 129S6/SvEvTac * C57BL/6 * FVB/N
Cell proliferation in the mandibular mesenchyme is reduced in Sox11tm1.1Gan/Sox11tm1.1Gan Tg(EIIa-cre)C5379Lmgd/0 embryosSox11tm1.1Gan/Sox11tm1.1Gan
Tg(EIIa-cre)C5379Lmgd/0		involves: 129S6/SvEvTac * C57BL/6 * FVB/N
Cell proliferation of the palatal shelf is reduced in Sox11tm1.1Gan/Sox11tm1.1Gan Tg(EIIa-cre)C5379Lmgd/0 miceSox11tm1.1Gan/Sox11tm1.1Gan
Tg(EIIa-cre)C5379Lmgd/0		involves: 129S6/SvEvTac * C57BL/6 * FVB/N
Skeletal abnormalities in Fgfr2tm2Ewj/Fgfr2+ Tg(EIIa-cre)C5379Lmgd/0 miceFgfr2tm2Ewj/Fgfr2+
Tg(EIIa-cre)C5379Lmgd/0		B6.Cg-Fgfr2tm2Ewj Tg(EIIa-cre)C5379Lmgd
Skull abnormalities in Fgfr2tm2Ewj/Fgfr2+ Tg(EIIa-cre)C5379Lmgd/0 miceFgfr2tm2Ewj/Fgfr2+
Tg(EIIa-cre)C5379Lmgd/0		B6.Cg-Fgfr2tm2Ewj Tg(EIIa-cre)C5379Lmgd
Skull analysis of Fgfr2tm2Ewj/Fgfr2+ Tg(EIIa-cre)C5379Lmgd/0 and Fgfr2tm1Ewj/Fgfr2+ Tg(EIIa-cre)C5379Lmgd/0 miceFgfr2tm2Ewj/Fgfr2+
Tg(EIIa-cre)C5379Lmgd/0		B6.Cg-Fgfr2tm2Ewj Tg(EIIa-cre)C5379Lmgd
Fgfr2tm1Ewj/Fgfr2+
Tg(EIIa-cre)C5379Lmgd/0		B6.Cg-Fgfr2tm1Ewj Tg(EIIa-cre)C5379Lmgd
Abnormal calvarial sutures in Fgfr2tm2Ewj/Fgfr2+ Tg(EIIa-cre)C5379Lmgd/0 miceFgfr2tm2Ewj/Fgfr2+
Tg(EIIa-cre)C5379Lmgd/0		B6.Cg-Fgfr2tm2Ewj Tg(EIIa-cre)C5379Lmgd
Abnormal proliferation, differentiation and no obvious change in apoptosis at the coronal suture in Fgfr2tm2Ewj/Fgfr2+ Tg(EIIa-cre)C5379Lmgd/0 miceFgfr2tm2Ewj/Fgfr2+
Tg(EIIa-cre)C5379Lmgd/0		B6.Cg-Fgfr2tm2Ewj Tg(EIIa-cre)C5379Lmgd
Abnormal proliferation and differentiation at the chondro-osseous junction and metaphysis in Fgfr2tm2Ewj/Fgfr2+ Tg(EIIa-cre)C5379Lmgd/0 miceFgfr2tm2Ewj/Fgfr2+
Tg(EIIa-cre)C5379Lmgd/0		B6.Cg-Fgfr2tm2Ewj Tg(EIIa-cre)C5379Lmgd
Dome-shaped skull of Fgfr2tm2Ewj/Fgfr2+ Tg(EIIa-cre)C5379Lmgd/0 miceFgfr2tm2Ewj/Fgfr2+
Tg(EIIa-cre)C5379Lmgd/0		B6.Cg-Fgfr2tm2Ewj Tg(EIIa-cre)C5379Lmgd
Postnatal growth retardation in Fgfr2tm2Ewj/Fgfr2+ Tg(EIIa-cre)C5379Lmgd/0 miceFgfr2tm2Ewj/Fgfr2+
Tg(EIIa-cre)C5379Lmgd/0		B6.Cg-Fgfr2tm2Ewj Tg(EIIa-cre)C5379Lmgd
Placenta abnormalities in Egfrtm1Dwt/Egfrtm1Dwt Tg(EIIa-cre)C5379Lmgd/0 miceEgfrtm1Dwt/Egfrtm1Dwt
Tg(EIIa-cre)C5379Lmgd/0		involves: 129S6/SvEvTac * C57BL/6J * FVB/N
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04/16/2024
MGI 6.23 		The Jackson Laboratory