Phenotype Images associated with this Allele - MGI

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Phenotype Images associated with this Allele

Nomenclature

Symbol:	Npc1^m1N
Name:	NPC intracellular cholesterol transporter 1; Niemann Pick type C1 NIH
MGI ID:	MGI:1857409
Synonyms:	CSD, lcsd, lysosomal cholesterol storage disease, nctr, -^npc, Npc-, NPC, NPC1, NPC1-, Npc1^N, npc1^NIH, npc^nih

Images for
Allele

Click images for details

Image	Caption	Genotypes involving this allele
Image	Caption	Allelic Composition	Genetic Background
	Abnormal morphology of Npc1^m1N/Npc1^m1N sperm	Npc1^m1N/Npc1^m1N	involves: BALB/c
	Analysis of Npc1^m1N/Npc1^m1N testes indicates partially blocked spermatogenesis	Npc1^m1N/Npc1^m1N	involves: BALB/c
	Neurodegenerative changes affecting cerebullar Purkinje cells of Npc1^m1N/Npc1^m1N, Npc2^tm1Plob/Npc2^tm1Plob, and double homozygous mice for Npc1^m1N and Npc2^tm1Plob	Npc1^m1N/Npc1^m1N	involves: 129S1/Sv * BALB/c * C57BL/6
		Npc2^tm1Plob/Npc2^tm1Plob	involves: 129S1/Sv * BALB/c * C57BL/6
		Npc1^m1N/Npc1^m1N Npc2^tm1Plob/Npc2^tm1Plob	involves: 129S1/Sv * BALB/c * C57BL/6

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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