Phenotype Images associated with this Allele - MGI

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Phenotype Images associated with this Allele

Nomenclature

Symbol:	Ngfr^tm1Jae
Name:	nerve growth factor receptor (TNFR superfamily, member 16); targeted mutation 1, Rudolf Jaenisch
MGI ID:	MGI:1857226
Synonyms:	Ngfr^-, NGFR^tm1Jac, p75-, p75e3-, p75^exonIII-, p75(III)^-, p75-KO, p75^NGFR, p75^NTR-, p75NTR-, p75^NTRexon3-null, p75NTR/ExonIII-, p75^NTR KO

Images for
Allele

Click images for details

Image	Caption	Genotypes involving this allele
		Allelic Composition	Genetic Background
	Adult Ngf^tm1.1Blhe/Ngf⁺ mice exhibit dilated cardiomyopathy and fibrosis and this phentoype is rescued in Ngfr^tm1Jae/Ngfr^tm1Jae Ngf^tm1.1Blhe/Ngf⁺ mice	Ngf^tm1.1Blhe/Ngf⁺	B6.Cg-Ngf^tm1.1Blhe
		Ngf^tm1.1Blhe/Ngf⁺ Ngfr^tm1Jae/Ngfr^tm1Jae	B6.Cg-Ngf^tm1.1Blhe Ngfr^tm1Jae
	Abnormalities in the microvasculature of hearts from Ngf^tm1.1Blhe/Ngf⁺ mice and rescue of the phenotype in Ngfr^tm1Jae/Ngfr^tm1Jae Ngf^tm1.1Blhe/Ngf⁺ mice	Ngf^tm1.1Blhe/Ngf⁺	B6.Cg-Ngf^tm1.1Blhe
		Ngf^tm1.1Blhe/Ngf⁺ Ngfr^tm1Jae/Ngfr^tm1Jae	B6.Cg-Ngf^tm1.1Blhe Ngfr^tm1Jae
	Reduced infarct size in Ngfr^tm1Jae/Ngfr^tm1Jae mice after cardiac ischemia-reperfusion surgery	Ngfr^tm1Jae/Ngfr^tm1Jae	B6.129S4-Ngfr^tm1Jae/J

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