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Phenotype Images associated with this Allele
Nomenclature
Symbol: Apoetm1Unc
Name: apolipoprotein E; targeted mutation 1, University of North Carolina
MGI ID: MGI:1857129
Synonyms: AopE(-), apoE-, apoE0, ApoE-KO, APOE KO, Apoetm1Un, epsilon-, mE-, mEKO
Images for
Allele
Click images for details
Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Decreased susceptibility to atherosclerosis in Apoetm1Unc/Apoetm1Unc Dp(17Nfkbil1-Olfr91)1Cogr/0 miceApoetm1Unc/Apoetm1Unc
Dp(17Nfkbil1-Olfr91)1Cogr/0
involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J
Morphology of aortic lesions in Apoetm1Unc/Apoetm1Unc and Apoetm1Unc/Apoetm1Unc Ttpatm1Far/Ttpatm1Far miceApoetm1Unc/Apoetm1Unc
Ttpatm1Far/Ttpatm1Far
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6
Apoetm1Unc/Apoetm1Uncinvolves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6
Cutaneous xanthomatosis and alopecia in Soat1tm1Ishi/Soat1tm1Ishi Apoetm1Unc/Apoetm1Unc and Soat1tm1Ishi/Soat1tm1Ishi Ldlrtm1Her/Ldlrtm1Her miceSoat1tm1Ishi/Soat1tm1Ishi
Apoetm1Unc/Apoetm1Unc
involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6
Soat1tm1Ishi/Soat1tm1Ishi
Ldlrtm1Her/Ldlrtm1Her
involves: 129S7/SvEvBrd * C57BL/6
Histopathology of cutaneous lesions developed in Soat1tm1Ishi/Soat1tm1Ishi Apoetm1Unc/Apoetm1Unc and Soat1tm1Ishi/Soat1tm1Ishi Ldlrtm1Her/Ldlrtm1Her mice fed high fat dietsSoat1tm1Ishi/Soat1tm1Ishi
Apoetm1Unc/Apoetm1Unc
involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6
Soat1tm1Ishi/Soat1tm1Ishi
Ldlrtm1Her/Ldlrtm1Her
involves: 129S7/SvEvBrd * C57BL/6
Apoetm1Unc/Apoetm1Unc Soat1tm1Far/Soat1tm1Far mice display severe xanthomatosisApoetm1Unc/Apoetm1Unc
Soat1tm1Far/Soat1tm1Far
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6J
Neutral lipid-poor atherosclerotic lesions in Apoetm1Unc/Apoetm1Unc Soat1tm1Far/Soat1tm1Far and Soat1tm1Far/Soat1tm1Far Ldlrtm1Her/Ldlrtm1Her miceApoetm1Unc/Apoetm1Unc
Soat1tm1Far/Soat1tm1Far
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6J
Ldlrtm1Her/Ldlrtm1Her
Soat1tm1Far/Soat1tm1Far
involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6J

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/23/2014
MGI 5.19
The Jackson Laboratory